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Genentech / jmpost

https://genentech.github.io/jmpost/
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Parameterization of GSF phi parameter #374

Closed gowerc closed 4 months ago

gowerc commented 4 months ago

A constant request from @mercifr1 is to use the logit-normal (see Kerioui et al. 2020 SiM) parameterisation for this parameter. Need to investigate the consequences of doing this with respect to the centered and non-centered parameterisations

gowerc commented 4 months ago

Ok, looks like I was wrong here, looks like centred and non-centered parameterisation is completely possible with the logit-normal parameterisation:

Centered: x ~ normal(mu, sigma) phi = logistic(x)

Non Cenered: eta ~ normal(0, 1) x = mu + eta * sigma phi = logistic(x)