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Gravitate-Health / focusing-manager

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Error in lens execution #19

Closed jkiddo closed 1 year ago

jkiddo commented 1 year ago

Please have a look at the following error:

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2023-09-10 00:02:45.444  INFO 37736 --- [nio-8080-exec-5] okhttp3.OkHttpClient                     : 
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tabletter"},"ingredient":[{"itemCodeableConcept":{"coding":[{"display":"PARACETAMOL"}]},"isActive":true,"strength":{"numerator":{"value":1000.0,"unit":"mg","system":"http://medicinpriser.dk/styrkeenhed","code":"MG"},"denominator":{"value":1,"unit":"filmovertrukne tabletter","system":"http://medicinpriser.dk/formbetegnelse","code":"TABFILM"}}}]}},{"fullUrl":"urn:oid:1e457a83-b375-4e63-9c9a-0c5e249ca238","resource":{"resourceType":"MedicationStatement","extension":[{"url":"http://medicinpriser.dk/indikation","valueCoding":{"system":"http://medicinpriser.dk/indikation","code":"145","display":"mod smerter"}}],"status":"active","medicationReference":{"reference":"urn:oid:276b6931-1a39-471f-b8cc-4aaa25195b1d"},"subject":{"reference":"urn:oid:5f78d9c1-8026-44fc-ab3c-a7f879225606"},"effectivePeriod":{"start":"2023-06-21T00:00:00+02:00"},"dosage":[{"extension":[{"url":"http://gravitatehealth.eu/fhir/StructureDefinition/gravitate-dosageperiod","valuePeriod":{"start":"2023-06-21T00:00:00+02:00"}}],"text":"1 tablet 4 gange daglig","route":{"coding":[{"system":"http://medicinpriser.dk/administrationsvej","code":"OR","display":"Oral anvendelse"}]}}]}},{"fullUrl":"urn:oid:73e4bde5-5c19-4d99-a52f-c9d47fda448c","resource":{"resourceType":"Medication","text":{"status":"generated","div":"\u003cdiv xmlns\u003d\"http://www.w3.org/1999/xhtml\"\u003e\u003cdiv class\u003d\"hapiHeaderText\"\u003eCalcichew-D3 Forte\u003c/div\u003e\u003c/div\u003e"},"extension":[{"url":"http://gravitatehealth.eu/fhir/StructureDefinition/gravitate-dk-package-leaflet-url","valueString":"https://www.indlaegssedler.dk/Search/Search/Search/73764"},{"url":"http://gravitatehealth.eu/fhir/StructureDefinition/gravitate-dk-package-number","valueString":"73764"},{"url":"https://www.indlaegssedler.dk/indlaegssedler/indlaegsseddel/","valueString":"https://www.indlaegssedler.dk/indlaegssedler/indlaegsseddel/73764"}],"identifier":[{"system":"urn:oid:2.16.724.4.8.10.200.10","value":"urn:oid:051ecfe4-ff22-40a7-a20d-17710072893a"}],"code":{"coding":[{"system":"http://www.whocc.no/atc","code":"A12AX","display":"Calcium, kombinationer med d-vitamin og/eller andre stoffer"},{"system":"http://medicinpriser.dk/drugid","code":"28105626815","display":"Calcichew-D3 Forte"}],"text":"Calcichew-D3 Forte"},"form":{"coding":[{"system":"http://medicinpriser.dk/formbetegnelse","code":"TYGTAB"}],"text":"tyggetabletter"},"ingredient":[{"itemCodeableConcept":{"coding":[{"display":"Calciumcarbonat"}]},"isActive":true,"strength":{"numerator":{"system":"http://medicinpriser.dk/styrkeenhed"},"denominator":{"value":1,"unit":"tyggetabletter","system":"http://medicinpriser.dk/formbetegnelse","code":"TYGTAB"}}},{"itemCodeableConcept":{"coding":[{"display":"Cholecalciferol"}]},"isActive":true,"strength":{"numerator":{"system":"http://medicinpriser.dk/styrkeenhed"},"denominator":{"value":1,"unit":"tyggetabletter","system":"http://medicinpriser.dk/formbetegnelse","code":"TYGTAB"}}}]}},{"fullUrl":"urn:oid:2ada188f-7d23-4d0f-b579-cdc7e4657aa6","resource":{"resourceType":"MedicationStatement","extension":[{"url":"http://medicinpriser.dk/indikation","valueCoding":{"system":"http://medicinpriser.dk/indikation","code":"291","display":"tilskud af kalk og vitamin D"}}],"status":"active","medicationReference":{"reference":"urn:oid:73e4bde5-5c19-4d99-a52f-c9d47fda448c"},"subject":{"reference":"urn:oid:5f78d9c1-8026-44fc-ab3c-a7f879225606"},"effectivePeriod":{"start":"2023-06-21T00:00:00+02:00"},"dosage":[{"extension":[{"url":"http://gravitatehealth.eu/fhir/StructureDefinition/gravitate-dosageperiod","valuePeriod":{"start":"2023-06-21T00:00:00+02:00"}}],"text":"1 tyggetablet morgen, middag, aften og nat","route":{"coding":[{"system":"http://medicinpriser.dk/administrationsvej","code":"OR","display":"Oral anvendelse"}]}}]}},{"fullUrl":"urn:oid:05c033de-443a-45c2-a056-83dd113cbe6a","resource":{"resourceType":"Medication","text":{"status":"generated","div":"\u003cdiv xmlns\u003d\"http://www.w3.org/1999/xhtml\"\u003e\u003cdiv class\u003d\"hapiHeaderText\"\u003eDovato\u003c/div\u003e\u003c/div\u003e"},"extension":[{"url":"http://gravitatehealth.eu/fhir/StructureDefinition/gravitate-dk-package-leaflet-url","valueString":"https://www.indlaegssedler.dk/Search/Search/Search/423096"},{"url":"http://gravitatehealth.eu/fhir/StructureDefinition/gravitate-dk-package-number","valueString":"423096"},{"url":"https://www.indlaegssedler.dk/indlaegssedler/indlaegsseddel/","valueString":"https://www.indlaegssedler.dk/indlaegssedler/indlaegsseddel/423096"}],"identifier":[{"system":"urn:oid:2.16.724.4.8.10.200.10","value":"urn:oid:9377d9cd-7895-45d8-82d3-bed20c1a4d15"},{"system":"https://www.gravitatehealth.eu/sid/doc","value":"EU/1/19/1370/001"}],"code":{"coding":[{"system":"http://www.whocc.no/atc","code":"J05AR25","display":"Lamivudin og dolutegravir"},{"system":"http://medicinpriser.dk/drugid","code":"28106176218","display":"Dovato"}],"text":"Dovato"},"form":{"coding":[{"system":"http://medicinpriser.dk/formbetegnelse","code":"TABFILM"}],"text":"filmovertrukne tabletter"},"ingredient":[{"itemCodeableConcept":{"coding":[{"display":"Dolutegravir"}]},"isActive":true,"strength":{"numerator":{"system":"http://medicinpriser.dk/styrkeenhed"},"denominator":{"value":1,"unit":"filmovertrukne tabletter","system":"http://medicinpriser.dk/formbetegnelse","code":"TABFILM"}}},{"itemCodeableConcept":{"coding":[{"display":"LAMIVUDIN"}]},"isActive":true,"strength":{"numerator":{"system":"http://medicinpriser.dk/styrkeenhed"},"denominator":{"value":1,"unit":"filmovertrukne tabletter","system":"http://medicinpriser.dk/formbetegnelse","code":"TABFILM"}}}]}},{"fullUrl":"urn:oid:5462b19a-f7e2-4889-a76f-a0866c506296","resource":{"resourceType":"MedicationStatement","extension":[{"url":"http://medicinpriser.dk/indikation","valueCoding":{"system":"http://medicinpriser.dk/indikation","code":"883","display":"mod hiv-infektion"}}],"status":"active","medicationReference":{"reference":"urn:oid:05c033de-443a-45c2-a056-83dd113cbe6a"},"subject":{"reference":"urn:oid:5f78d9c1-8026-44fc-ab3c-a7f879225606"},"effectivePeriod":{"start":"2023-06-21T00:00:00+02:00"},"dosage":[{"text":"Tages efter skriftlig anvisning fra afdeling","route":{"coding":[{"system":"http://medicinpriser.dk/administrationsvej","code":"OR","display":"Oral anvendelse"}]}}]}}]}}
2023-09-10 00:02:45.445  INFO 37736 --- [nio-8080-exec-5] okhttp3.OkHttpClient                     : --> END POST (42133-byte body)
2023-09-10 00:02:45.934  INFO 37736 --- [nio-8080-exec-5] okhttp3.OkHttpClient                     : <-- 500 https://fosps.gravitatehealth.eu/focusing/focus/bundlepackageleaflet-6eb523b7a88cd6dcee848368833cbd08 (488ms)
2023-09-10 00:02:45.937  INFO 37736 --- [nio-8080-exec-5] okhttp3.OkHttpClient                     : x-powered-by: Express
2023-09-10 00:02:45.938  INFO 37736 --- [nio-8080-exec-5] okhttp3.OkHttpClient                     : content-type: application/json; charset=utf-8
2023-09-10 00:02:45.938  INFO 37736 --- [nio-8080-exec-5] okhttp3.OkHttpClient                     : content-length: 49
2023-09-10 00:02:45.938  INFO 37736 --- [nio-8080-exec-5] okhttp3.OkHttpClient                     : etag: W/"31-8gcrqyTVmF7XOIyKuM9W0c7xN2A"
2023-09-10 00:02:45.938  INFO 37736 --- [nio-8080-exec-5] okhttp3.OkHttpClient                     : date: Sat, 09 Sep 2023 22:02:45 GMT
2023-09-10 00:02:45.938  INFO 37736 --- [nio-8080-exec-5] okhttp3.OkHttpClient                     : x-envoy-upstream-service-time: 300
2023-09-10 00:02:45.939  INFO 37736 --- [nio-8080-exec-5] okhttp3.OkHttpClient                     : server: istio-envoy
2023-09-10 00:02:45.940  INFO 37736 --- [nio-8080-exec-5] okhttp3.OkHttpClient                     : 
2023-09-10 00:02:45.941  INFO 37736 --- [nio-8080-exec-5] okhttp3.OkHttpClient                     : {"message":"Error in lens execution","reason":{}}
jkiddo commented 1 year ago

FYI - @amedranogil this is blocking

10alejospain commented 1 year ago

I can't replicate the error. I tried with the IPS provided by you and the same ePI. I trined with an specific preprocessor and without it and still it won't give me a 500.

Can you try again and share the err log if it persist?

jkiddo commented 1 year ago 
2023-09-11 10:07:02.236  INFO 58840 --- [nio-8080-exec-1] okhttp3.OkHttpClient                     : --> POST https://fosps.gravitatehealth.eu/focusing/focus/bundlepackageleaflet-6eb523b7a88cd6dcee848368833cbd08
2023-09-11 10:07:02.237  INFO 58840 --- [nio-8080-exec-1] okhttp3.OkHttpClient                     : Content-Length: 1602
2023-09-11 10:07:02.237  INFO 58840 --- [nio-8080-exec-1] okhttp3.OkHttpClient                     : Accept: application/json
2023-09-11 10:07:02.237  INFO 58840 --- [nio-8080-exec-1] okhttp3.OkHttpClient                     : Content-Type: application/json
2023-09-11 10:07:02.237  INFO 58840 --- [nio-8080-exec-1] okhttp3.OkHttpClient                     : Authorization: Bearer eyJhbGciOiJSUzI1NiIsInR5cCIgOiAiSldUIiwia2lkIiA6ICJkTEdtcGNiNTNHN3FTODc3dEYxUGdHaV94Qi1fdWtPb05oOXo5cmdFckhjIn0.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.KcLKNKiTXOx984rDBYB9YXsS_dwL4WqrGtbaALgxuuGnnC_TL1iqDD5wS6XKFjhKtbn4vgMXjVEYvrlaFgTTC_0DZZen8T2P1o_5fDKshMPK27IrL7_u31qk8yj6oNDi5wQpvJfC7I0YYMVw5oWB7CC1Hef9cdKPyVthkBjCwu6fM3RpA98ylUIvsgipj2Z88qEBzxhEIk6zRjfhPys7HMWIBzuyTMXZy80n7GnxBMFxjxkVBQLySdwu63j8yKWv_tPZpUvhF8LEsy-y_KdDJ3IjXy0P8IUuai9XXd13CO1_uhNc3vEHGj1PnpTP7S_EkIH_xPR7QQMEMI9krtfMpg
2023-09-11 10:07:02.237  INFO 58840 --- [nio-8080-exec-1] okhttp3.OkHttpClient                     : User-Agent: OpenAPI-Generator/MVP2/java
2023-09-11 10:07:02.237  INFO 58840 --- [nio-8080-exec-1] okhttp3.OkHttpClient                     : 
2023-09-11 10:07:02.238  INFO 58840 --- [nio-8080-exec-1] okhttp3.OkHttpClient                     : {"ips":{"resourceType":"Bundle","meta":{"lastUpdated":"2023-09-11T08:07:01.473+00:00"},"identifier":{"system":"urn:oid:2.16.724.4.8.10.200.10","value":"17f8bcb7-06d0-42ef-acdb-d2f249b6534d"},"type":"document","timestamp":"2023-09-11T08:07:01.473+00:00","entry":[{"fullUrl":"20f4384a-00bf-4f54-a586-4dede986fddf","resource":{"resourceType":"Composition","id":"20f4384a-00bf-4f54-a586-4dede986fddf","status":"final","subject":{"reference":"Patient/37478061-c5bf-35ce-9fd7-b981a6f53f97"},"date":"2023-09-11T08:07:01+00:00","title":"Patient Summary as of Mon Sep 11 08:07:01 GMT 2023","section":[{"title":"Medication Summary","code":{"coding":[{"system":"http://loinc.org","code":"10160-0","display":"History of Medication use Narrative"}]}},{"title":"Immunizations","code":{"coding":[{"system":"http://loinc.org","code":"11369-6","display":"History of Immunization Narrative"}]}}]}},{"fullUrl":"37478061-c5bf-35ce-9fd7-b981a6f53f97","resource":{"resourceType":"Patient","id":"37478061-c5bf-35ce-9fd7-b981a6f53f97","meta":{"source":"https://services.nsi.dk/en/Services/FMK","profile":["http://hl7.org/fhir/uv/ipa/StructureDefinition/ipa-patient","http://hl7.org/fhir/uv/ips/StructureDefinition/Patient-uv-ips","http://hl7.dk/fhir/core/StructureDefinition/dk-core-patient"]},"identifier":[{"use":"official","system":"urn:oid:1.2.208.176.1.2","value":"2502889861"}],"active":true,"name":[{"use":"official","family":"Knudsen","given":["Knud","Gravitate"]}],"gender":"unknown","birthDate":"1988-02-25","address":[{"type":"both","line":["Islands Brygge 405, "],"district":"Søllested","postalCode":"4920"}]}}]}}
2023-09-11 10:07:02.238  INFO 58840 --- [nio-8080-exec-1] okhttp3.OkHttpClient                     : --> END POST (1602-byte body)
2023-09-11 10:07:02.752  INFO 58840 --- [nio-8080-exec-1] okhttp3.OkHttpClient                     : <-- 500 https://fosps.gravitatehealth.eu/focusing/focus/bundlepackageleaflet-6eb523b7a88cd6dcee848368833cbd08 (513ms)
2023-09-11 10:07:02.753  INFO 58840 --- [nio-8080-exec-1] okhttp3.OkHttpClient                     : x-powered-by: Express
2023-09-11 10:07:02.753  INFO 58840 --- [nio-8080-exec-1] okhttp3.OkHttpClient                     : content-type: application/json; charset=utf-8
2023-09-11 10:07:02.753  INFO 58840 --- [nio-8080-exec-1] okhttp3.OkHttpClient                     : content-length: 49
2023-09-11 10:07:02.753  INFO 58840 --- [nio-8080-exec-1] okhttp3.OkHttpClient                     : etag: W/"31-8gcrqyTVmF7XOIyKuM9W0c7xN2A"
2023-09-11 10:07:02.754  INFO 58840 --- [nio-8080-exec-1] okhttp3.OkHttpClient                     : date: Mon, 11 Sep 2023 08:07:02 GMT
2023-09-11 10:07:02.754  INFO 58840 --- [nio-8080-exec-1] okhttp3.OkHttpClient                     : x-envoy-upstream-service-time: 403
2023-09-11 10:07:02.754  INFO 58840 --- [nio-8080-exec-1] okhttp3.OkHttpClient                     : server: istio-envoy
2023-09-11 10:07:02.755  INFO 58840 --- [nio-8080-exec-1] okhttp3.OkHttpClient                     : 
2023-09-11 10:07:02.757  INFO 58840 --- [nio-8080-exec-1] okhttp3.OkHttpClient                     : {"message":"Error in lens execution","reason":{}}
2023-09-11 10:07:02.764  INFO 58840 --- [nio-8080-exec-1] okhttp3.OkHttpClient                     : <-- END HTTP (49-byte body)

Same error

jkiddo commented 1 year ago

And with an even richer IPS:

2023-09-11 10:16:23.160  INFO 59468 --- [nio-8080-exec-4] okhttp3.OkHttpClient                     : --> POST https://fosps.gravitatehealth.eu/focusing/focus/bundlepackageleaflet-6eb523b7a88cd6dcee848368833cbd08
2023-09-11 10:16:23.161  INFO 59468 --- [nio-8080-exec-4] okhttp3.OkHttpClient                     : Content-Length: 42133
2023-09-11 10:16:23.161  INFO 59468 --- [nio-8080-exec-4] okhttp3.OkHttpClient                     : Accept: application/json
2023-09-11 10:16:23.161  INFO 59468 --- [nio-8080-exec-4] okhttp3.OkHttpClient                     : Content-Type: application/json
2023-09-11 10:16:23.162  INFO 59468 --- [nio-8080-exec-4] okhttp3.OkHttpClient                     : Authorization: Bearer eyJhbGciOiJSUzI1NiIsInR5cCIgOiAiSldUIiwia2lkIiA6ICJkTEdtcGNiNTNHN3FTODc3dEYxUGdHaV94Qi1fdWtPb05oOXo5cmdFckhjIn0.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.bRl7BNQ36i2VzMSXF_Rkwi00yahN69jZpPb54lfDFBqifPOqnlZx26216vx_jV6t_G9l_-oYTGJ7ZcgMhpdoaXPPMh1ggyLRIkwYbUIdtSo8uMK6iplNUjFYQfXzuBMqp-JcE6WCZHdLqsb-Id8GuggHp63eh7TeS-cLEd_bFS9_2LQzXbyaDaYCGxo2ynhxSgxreF2vFJwmlWqnUBbyVl7JNQoM2wNyaKQenaMDeN7rgym4FTb7MwHtiTutlZfKLeHWP2fNeDc5iVoIt6qAo3iQR5yMbZwx_5rcYYVjjrz_l8gyoaTiCHkC_IaX3L_OEYWONPyYl9xWpY1x56nhdA
2023-09-11 10:16:23.162  INFO 59468 --- [nio-8080-exec-4] okhttp3.OkHttpClient                     : User-Agent: OpenAPI-Generator/MVP2/java
2023-09-11 10:16:23.162  INFO 59468 --- [nio-8080-exec-4] okhttp3.OkHttpClient                     : 
2023-09-11 10:16:23.162  INFO 59468 --- [nio-8080-exec-4] okhttp3.OkHttpClient                     : {"ips":{"resourceType":"Bundle","meta":{"lastUpdated":"2023-09-11T10:16:20.973+02:00"},"language":"da","identifier":{"system":"urn:oid:2.16.724.4.8.10.200.10","value":"urn:oid:abb4c8e0-d4e1-4846-a545-414ab201f38c"},"type":"document","timestamp":"2023-09-11T10:16:20.973+02:00","entry":[{"fullUrl":"urn:oid:b08b9ff1-57ae-443d-be54-bb6f0fde2cd5","resource":{"resourceType":"Composition","status":"final","type":{"coding":[{"system":"http://loinc.org","code":"60591-5","display":"Patient summary Document"}]},"subject":{"reference":"urn:oid:adaaf982-30f2-4825-a3fc-a721d7c28d48"},"date":"2023-09-11T10:16:20+02:00","author":[{"display":"Lars Larsen"}],"title":"Patient Summary as of Mon Sep 11 10:16:20 CEST 2023","section":[{"title":"Medication","code":{"coding":[{"system":"http://loinc.org","code":"10160-0","display":"History of Medication use 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2023-09-11 10:16:23.589  INFO 59468 --- [nio-8080-exec-4] okhttp3.OkHttpClient                     : <-- 500 https://fosps.gravitatehealth.eu/focusing/focus/bundlepackageleaflet-6eb523b7a88cd6dcee848368833cbd08 (426ms)
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2023-09-11 10:16:23.589  INFO 59468 --- [nio-8080-exec-4] okhttp3.OkHttpClient                     : etag: W/"31-8gcrqyTVmF7XOIyKuM9W0c7xN2A"
2023-09-11 10:16:23.589  INFO 59468 --- [nio-8080-exec-4] okhttp3.OkHttpClient                     : date: Mon, 11 Sep 2023 08:16:23 GMT
2023-09-11 10:16:23.589  INFO 59468 --- [nio-8080-exec-4] okhttp3.OkHttpClient                     : x-envoy-upstream-service-time: 288
2023-09-11 10:16:23.590  INFO 59468 --- [nio-8080-exec-4] okhttp3.OkHttpClient                     : server: istio-envoy
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2023-09-11 10:16:23.591  INFO 59468 --- [nio-8080-exec-4] okhttp3.OkHttpClient                     : {"message":"Error in lens execution","reason":{}}
2023-09-11 10:16:23.591  INFO 59468 --- [nio-8080-exec-4] okhttp3.OkHttpClient                     : <-- END HTTP (49-byte body)
jkiddo commented 1 year ago

@10alejospain there you go. Still errors

10alejospain commented 1 year ago

We discovered a problem with the pregnancy lens that return some sort of error when no gender is avaible in the IPS. We are working to solve it now. Try to apply only one lens to test it.

jkiddo commented 1 year ago

I just added gender to the IPS (see example below). I still get an error:

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2023-09-12 12:56:13.253  INFO 92728 --- [nio-8080-exec-3] okhttp3.OkHttpClient                     : Authorization: Bearer eyJhbGciOiJSUzI1NiIsInR5cCIgOiAiSldUIiwia2lkIiA6ICJkTEdtcGNiNTNHN3FTODc3dEYxUGdHaV94Qi1fdWtPb05oOXo5cmdFckhjIn0.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.aiAg-YFxXVlXtxQ3peNrD5yjLqY8mlNIS_ZOof4ZYnkK6L16hPCXWEoes6OOOKTU1lCZH2nyzmKfY57RV8IZyNPOIOoRG8yW5fG5EHWS1-g3XfYJx0_xWsH0s3oqZSWekYU0ImtXqAISOYwvmxZt0eNbjBO1yIILMZGHauEt114ajmPB7UjN68II_omWo0oQqoVMUP82I8HaFcP1q3dUn0LX99GF2BACSd98sYK2KUfVqQbK4vzXOHboBXKjATGMj4UGQh_i2KUkcSEfjjiflFjmbgsOFub_VskLJ99YXNAL5T933KIqc1bzafHIPmDeBZ907vNfLF_nTqbgT430ng
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2023-09-12 12:56:13.257  INFO 92728 --- [nio-8080-exec-3] okhttp3.OkHttpClient                     : {"ips":{"resourceType":"Bundle","meta":{"lastUpdated":"2023-09-12T12:55:52.494+02:00"},"language":"da","identifier":{"system":"urn:oid:2.16.724.4.8.10.200.10","value":"urn:oid:761bd56f-20a5-428a-854d-b24086cbf05a"},"type":"document","timestamp":"2023-09-12T12:55:52.494+02:00","entry":[{"fullUrl":"urn:oid:36725278-d43b-4a1a-9f2a-6459625bb453","resource":{"resourceType":"Composition","status":"final","type":{"coding":[{"system":"http://loinc.org","code":"60591-5","display":"Patient summary Document"}]},"subject":{"reference":"urn:oid:a2a2e628-acce-48a1-95ac-66ec5b24d835"},"date":"2023-09-12T12:55:52+02:00","author":[{"display":"Lars Larsen"}],"title":"Patient Summary as of Tue Sep 12 12:55:52 CEST 2023","section":[{"title":"Medication","code":{"coding":[{"system":"http://loinc.org","code":"10160-0","display":"History of Medication use 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hårde"},"ingredient":[{"itemCodeableConcept":{"coding":[{"display":"ORLISTAT"}]},"isActive":true,"strength":{"numerator":{"value":120.0,"unit":"mg","system":"http://medicinpriser.dk/styrkeenhed","code":"MG"},"denominator":{"value":1,"unit":"kapsler, hårde","system":"http://medicinpriser.dk/formbetegnelse","code":"KAPH"}}}]}},{"fullUrl":"urn:oid:1c102028-1622-4629-90de-2f50cea70856","resource":{"resourceType":"MedicationStatement","extension":[{"url":"http://medicinpriser.dk/indikation","valueCoding":{"system":"http://medicinpriser.dk/indikation","code":"341","display":"vægtreducerende"}}],"status":"active","medicationReference":{"reference":"urn:oid:67b67285-8e02-46f6-b811-ab57938e6396"},"subject":{"reference":"urn:oid:a2a2e628-acce-48a1-95ac-66ec5b24d835"},"effectivePeriod":{"start":"2023-06-21T00:00:00+02:00"},"dosage":[{"extension":[{"url":"http://gravitatehealth.eu/fhir/StructureDefinition/gravitate-dosageperiod","valuePeriod":{"start":"2023-06-21T00:00:00+02:00"}}],"text":"1 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2023-09-12 12:56:13.258  INFO 92728 --- [nio-8080-exec-3] okhttp3.OkHttpClient                     : --> END POST (42149-byte body)
2023-09-12 12:56:13.917  INFO 92728 --- [nio-8080-exec-3] okhttp3.OkHttpClient                     : <-- 500 https://fosps.gravitatehealth.eu/focusing/focus/bundlepackageleaflet-6eb523b7a88cd6dcee848368833cbd08 (657ms)
2023-09-12 12:56:13.918  INFO 92728 --- [nio-8080-exec-3] okhttp3.OkHttpClient                     : x-powered-by: Express
2023-09-12 12:56:13.919  INFO 92728 --- [nio-8080-exec-3] okhttp3.OkHttpClient                     : content-type: application/json; charset=utf-8
2023-09-12 12:56:13.920  INFO 92728 --- [nio-8080-exec-3] okhttp3.OkHttpClient                     : content-length: 49
2023-09-12 12:56:13.920  INFO 92728 --- [nio-8080-exec-3] okhttp3.OkHttpClient                     : etag: W/"31-8gcrqyTVmF7XOIyKuM9W0c7xN2A"
2023-09-12 12:56:13.921  INFO 92728 --- [nio-8080-exec-3] okhttp3.OkHttpClient                     : date: Tue, 12 Sep 2023 10:56:13 GMT
2023-09-12 12:56:13.922  INFO 92728 --- [nio-8080-exec-3] okhttp3.OkHttpClient                     : x-envoy-upstream-service-time: 285
2023-09-12 12:56:13.922  INFO 92728 --- [nio-8080-exec-3] okhttp3.OkHttpClient                     : server: istio-envoy
2023-09-12 12:56:13.923  INFO 92728 --- [nio-8080-exec-3] okhttp3.OkHttpClient                     : 
2023-09-12 12:56:13.924  INFO 92728 --- [nio-8080-exec-3] okhttp3.OkHttpClient                     : {"message":"Error in lens execution","reason":{}}
2023-09-12 12:56:13.925  INFO 92728 --- [nio-8080-exec-3] okhttp3.OkHttpClient                     : <-- END HTTP (49-byte body)
jkiddo commented 1 year ago

@10alejospain I have no use case for picking out a specific lens. I'd like them all to be executed.

10alejospain commented 1 year ago

I hope it to be ready for tomorrow, but we need some time to clear the subyacent problems that we encountered while solving this bug. The ePI that you are using that is in english is retrieving a spanish version because some misscomunication on different languages for the same ePI.

jkiddo commented 1 year ago

In addition - @10alejospain I think the API could be improved by letting the client send the document identifer and a language instead of the id.

10alejospain commented 1 year ago

Yes, it's spected to change to that format soon. Using the identifiers (the EMA ones for example) will happen as soon as we are able to implement it.

@jkiddo Also we noticed that the _language FHIR query is not working properly for us. Example: https://fosps.gravitatehealth.eu/epi/api/fhir/Bundle?_language=es Idk if it has something to do with a bugged version.

aalonsolopez commented 1 year ago

The actual error is identified. There is a problem with that EPI (dovato) that is relationed with an EPI with "preprocessed" status, when it's not. We are working on that now.

jkiddo commented 1 year ago

Ill need a date/time for when its fixed

aalonsolopez commented 1 year ago

Well, I expect to have it solved in the next few days. I would like to have it solved today, but IDK if it will be possible.

aalonsolopez commented 1 year ago

Solved faster than i thought, but there's something to explain. processedbundledovato-en have annotations, but not where they should be, and we can't fix that. What I can say is that we have a first version of automatic preprocessing service that will be deployed in the next few days.

@jkiddo report anything you see that we can fix

aalonsolopez commented 1 year ago

Sorry I missclicked

aalonsolopez commented 1 year ago

@joofio can you please look the https://fosps.gravitatehealth.eu/epi/api/fhir/Bundle/processedbundledovato-en annotations to fix them? the failures are at the spans with "pregnancyCategory" and "breastfeedingCategory" classes.

Thank you in advance!

jkiddo commented 1 year ago

@joofio the identifier on https://fosps.gravitatehealth.eu/epi/api/fhir/Bundle/processedbundledovato-en (EU/1/97/049/001) is for karvea - not dovato. That needs fixing as well. It should have the identifiers listed in https://www.ema.europa.eu/en/documents/all-authorised-presentations/dovato-epar-all-authorised-presentations_en.pdf

jkiddo commented 1 year ago

FYI - I've fixed the EN and ES versions manually on the FOSPS environment my self.

jkiddo commented 1 year ago

@aalonsolopez now I get a new error:

2023-09-14 16:03:19.407  INFO 33598 --- [nio-8080-exec-2] okhttp3.OkHttpClient                     : --> POST https://fosps.gravitatehealth.eu/focusing/focus/processedbundledovato-en
2023-09-14 16:03:19.408  INFO 33598 --- [nio-8080-exec-2] okhttp3.OkHttpClient                     : Content-Length: 42149
2023-09-14 16:03:19.408  INFO 33598 --- [nio-8080-exec-2] okhttp3.OkHttpClient                     : Accept: application/json
2023-09-14 16:03:19.408  INFO 33598 --- [nio-8080-exec-2] okhttp3.OkHttpClient                     : Content-Type: application/json
2023-09-14 16:03:19.408  INFO 33598 --- [nio-8080-exec-2] okhttp3.OkHttpClient                     : Authorization: Bearer eyJhbGciOiJSUzI1NiIsInR5cCIgOiAiSldUIiwia2lkIiA6ICJkTEdtcGNiNTNHN3FTODc3dEYxUGdHaV94Qi1fdWtPb05oOXo5cmdFckhjIn0.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.T2biKnWzMmp-mx0WR-utZmwZt7CAWcd9tZ4m6XYrjPANjDNzAt1p7n4nlcAwoSWOH9Xb1lQhnea-k7GIxGHRHD8sAXSA-ORzA1UWBV4ogrfZ8syXntVMOfZYQlx6UU8ksKKS_SUmbEg_WJfqAoz0R7k0A1dh4bOGvN3ioh9Hz2Szdvgaf3SjW_NyoUyU568OVFH1pR3sJ0p7o4jPjN2YK5EGC8pk4KKK7MLRVefRR-kLS-JdTUZVb8Ajn3NG6QRzRFxeDy6noP51c7oDiWHciINdQmH3HcHO2lh_Bbr-qBLvDLcR5R-OceSXRZfbCcUJ1jvVCU-_lz_akIodN4vJ7Q
2023-09-14 16:03:19.408  INFO 33598 --- [nio-8080-exec-2] okhttp3.OkHttpClient                     : User-Agent: OpenAPI-Generator/MVP2/java
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Package Leaflet","code":{"coding":[{"system":"https://spor.ema.europa.eu/rmswi/","code":"100000155538"}],"text":"B. PACKAGE LEAFLET"},"text":{"status":"additional","div":"<div xmlns=\"http://www.w3.org/1999/xhtml\">Package leaflet: Information for the patient Dovato 50 mg/300 mg film-coated tablets dolutegravir/lamivudine Read all of this leaflet carefully before you start taking this medicine because it contains important information for you.<ul><li>Keep this leaflet. You may need to read it again.</li><li>If you have any further questions, ask your doctor or pharmacist.</li><li>This medicine has been prescribed for you only. Do not pass it on to others. It may harm them, even if their signs of illness are the same as yours.</li><li>If you get any side effects talk to your doctor or pharmacist. This includes any possible side effects not listed in this leaflet. See section 4.</li></ul></div>"},"section":[{"title":"Package leaflet: Information for the user","code":{"coding":[{"system":"https://spor.ema.europa.eu/rmswi/","code":"100000155538"}],"text":"Package leaflet: Information for the user"},"text":{"status":"additional","div":"<samplePreprocessTag><samplePreprocessTag3><div xmlns=\"http://www.w3.org/1999/xhtml\"><p><strong>Dovato 50 mg/300 mg film-coated tablets</strong></p><p><em>dolutegravir/lamivudine</em></p><p><strong>Read all of this leaflet carefully before you start taking this medicine because it contains important information for you.</strong></p><ul><li>Keep this leaflet. You may need to read it again.</li><li>If you have any further questions, ask your doctor, or pharmacist.</li><li>This medicine has been prescribed for you only. Do not pass it on to others. It may harm them, even if their signs of illness are the same as yours.</li><li>If you get any side effects, talk to your doctor, or pharmacist. This includes any possible side effects not listed in this leaflet. See section 4.</li></ul></div></samplePreprocessTag></samplePreprocessTag3>"}},{"title":"What is in this leaflet","code":{"coding":[{"system":"https://spor.ema.europa.eu/rmswi/","code":"100000155538"}],"text":"What is in this leaflet"},"text":{"status":"additional","div":"<samplePreprocessTag><samplePreprocessTag3><div xmlns=\"http://www.w3.org/1999/xhtml\">What in this leaflet<ol><li>What Dovato is and what it is used for</li><li>What you need to know before you take Dovato</li><li>How to take Dovato</li><li>Possible side effects</li><li>How to store Dovato</li><li>Contents of the pack and other information</li></ol></div></samplePreprocessTag></samplePreprocessTag3>"}},{"title":"1. What Dovato 50 mg/300 mg film-coated tablets is and what it is used for","code":{"coding":[{"system":"https://spor.ema.europa.eu/rmswi/","code":"100000155538"}],"text":"1. What Dovato 50 mg/300 mg film-coated tablets is and what it is used for"},"text":{"status":"additional","div":"<samplePreprocessTag><samplePreprocessTag3><div xmlns=\"http://www.w3.org/1999/xhtml\"><p>Dovato is a medicine that contains two active ingredients used to treat human immunodeficiency virus (HIV) infection: dolutegravir and lamivudine. Dolutegravir belongs to a group of anti-retroviral medicines called integrase inhibitors (INIs), and lamivudine belongs to a group of anti-retroviral medicines called nucleoside analogue reverse transcriptase inhibitors (NRTIs).</p><span class=\"indication\"></span><p>Dovato is used to treat HIV in adults and adolescents over 12 years old who weigh at least 40 kg.</p><p>Dovato does not cure HIV infection; it keeps the amount of virus in your body at a low level. This helps maintain the number of CD4 cells in your blood. CD4 cells are a type of white blood cells that are important in helping your body to fight infection.</p><p>Not everyone responds to treatment with Dovato in the same way. Your doctor will monitor the effectiveness of your treatment.</p></div></samplePreprocessTag></samplePreprocessTag3>"}},{"title":"2. What you need to know before you take Dovato 50 mg/300 mg film-coated tablets","code":{"coding":[{"system":"https://spor.ema.europa.eu/rmswi/","code":"100000155538"}],"text":"2. What you need to know before you take Dovato 50 mg/300 mg film-coated tablets"},"text":{"status":"additional","div":"<samplePreprocessTag><samplePreprocessTag3><div xmlns=\"http://www.w3.org/1999/xhtml\"><p>Do not take Dovato</p><ul><li>if you are allergic (hypersensitive) to dolutegravir or lamivudine or any of the other ingredients of this medicine (listed in section 6).</li><li>If you are taking a medicine called fampridine (also known as dalfampridine; used in multiple sclerosis).</li><li>If you think any of these apply to you, tell your doctor. Warnings and precautions Some people taking Dovato or other combination treatments for HIV are more at risk of serious side effects than others. You need to be aware of the extra risks:</li><li><span class=\"liver\">if you have moderate or severe liver disease </span>if you have ever had liver disease, including hepatitis B or C (if you have hepatitis B infection, don’t stop Dovato without your doctor’s advice, as your hepatitis may come back) • if you have a kidney problem. → Talk to your doctor before using Dovato if any of these apply to you. You may need extra checkups, including blood tests, while you’re taking your medicine. See section 4 for more information. Allergic reactions Dovato contains dolutegravir. Dolutegravir can cause a serious allergic reaction known as a hypersensitivity reaction. You need to know about important signs and symptoms to look out for while you’re taking Dovato. → Read the information ‘Allergic reactions’ in section 4 of this leaflet. Look out for important symptoms Some people taking medicines for HIV infection develop other conditions, which can be serious. These include: • symptoms of infections and inflammation • joint pain, stiffness and bone problems. You need to know about important signs and symptoms to look out for while you’re taking Dovato. → Read the information ‘Other possible side effects’ in section 4 of this leaflet.</li></ul><p><strong>Children</strong></p><p>This medicine is not for use in children under 12 years of age, because it has not been studied in these patients.</p><p><strong>Other medicines and Dovato</strong></p><p>Tell your doctor if you are taking, have recently taken or might take any other medicines.</p><p>Don't take Dovato with the following medicine:</p><ul><li>fampridine (also known as dalfampridine), used in <strong>multiple sclerosis.</strong></li></ul><p>Some medicines can affect how Dovato works or make it more likely that you will have side effects. Dovato can also affect how some other medicines work.</p><p>Tell your doctor if you are taking any of the medicines in the following list:</p><ul><li>metformin, to treat diabetes</li><li>medicines called antacids, to treat indigestion and heartburn. Do not take an antacid during the 6 hours before you take Dovato, or for at least 2 hours after you take it (see also section 3, ‘How to take Dovato’)</li><li>supplements or multivitamins containing calcium, iron or magnesium. If you take Dovato with food, you can take supplements or multivitamins containing calcium, iron or magnesium at the same time as Dovato. If you do not take Dovato with food, do not take a supplement or multivitamin containing calcium, iron or magnesium during the 6 hours before you take Dovato, or for at least 2 hours after you take it (see also section 3, ‘How to take Dovato’)</li><li>emtricitabine, etravirine, efavirenz, nevirapine or tipranavir/ritonavir, to treat HIV infection</li><li>medicines (usually liquids) containing sorbitol and other sugar alcohols (such as xylitol, mannitol, lactitol or maltitol), if taken regularly</li><li>cladribine, to treat leukaemia or multiple sclerosis</li><li>rifampicin, to treat tuberculosis (TB) and other bacterial infections</li><li>phenytoin and phenobarbital, to treat epilepsy</li><li>oxcarbazepine and carbamazepine, to treat epilepsy or bipolar disorder</li><span class=\"contra-indication-hypericum\"></span><li><p>St. John’s wort (Hypericum perforatum), a herbal remedy to treat depression.</p></li><li><p>Tell your doctor or pharmacist if you are taking any of these. Your doctor may decide to adjust your dose or that you need extra check ups.</p></li></ul><span class=\"pregnancyCategory highlight\"></span><p><strong>Pregnancy</strong></p><p>If you are pregnant, think you may be pregnant, or if you are planning to have a baby:</p><ul><li>Talk to your doctor about the risks and benefits of taking Dovato.</li></ul><p>Taking Dovato at the time of becoming pregnant or during the first six weeks of pregnancy, may increase the risk of a birth defect, called neural tube defect, such as spina bifida (malformed spinal cord).</p><p>If you could get pregnant while taking Dovato:</p><ul><li>Talk to your doctor and discuss whether there is a need for contraception, such as condom or pills.</li></ul><p>Tell your doctor immediately if you become pregnant or are planning to become pregnant. Your doctor will review your treatment. Do not stop taking Dovato without consulting your doctor, as this may harm you and your unborn child.</p><p><strong>Breast-feeding</strong></p><p>Breast-feeding is not recommended in women living with HIV because HIV infection can be passed on to the baby in breast milk. A small amount of the ingredients in Dovato can also pass into your breast milk. If you are breast-feeding, or thinking about breast-feeding, you should discuss it with your doctor as soon as possible.</p><p><strong>Driving and using machines</strong></p><p>Dovato can make you dizzy, and have other side effects that make you less alert.</p><ul><li>Don’t drive or operate machinery unless you are sure you’re not affected.</li></ul></div></samplePreprocessTag></samplePreprocessTag3>"}},{"title":"3. How to take Dovato 50 mg/300 mg film-coated tablets","code":{"coding":[{"system":"https://spor.ema.europa.eu/rmswi/","code":"100000155538"}],"text":"3. How to take Dovato 50 mg/300 mg film-coated tablets"},"text":{"status":"additional","div":"<samplePreprocessTag><samplePreprocessTag3><div xmlns=\"http://www.w3.org/1999/xhtml\"><p>Always take this medicine exactly as your doctor has told you. Check with your doctor or pharmacist if you are not sure.</p><ul><li>The recommended dose of Dovato is one tablet once a day.</li></ul><p>Swallow the tablet with some liquid. Dovato can be taken with or without food.</p><p><strong>Use in adolescents</strong></p><p>Adolescents aged between 12 and 17 years and weighing at least 40 kg can take the adult dose of one tablet once a day.</p><p><strong>Antacid medicines</strong></p><p>Antacids, to treat indigestion and heartburn, can stop Dovato being absorbed into your body and make it less effective. Do not take an antacid during the 6 hours before you take Dovato, or for at least 2 hours after you take it. You can take other acid-lowering medicines like ranitidine and omeprazole at the same time as Dovato.</p><ul><li>Talk to your doctor for further advice on taking acid-lowering medicines with Dovato.</li></ul><p><strong>Supplements or multivitamins containing calcium, iron or magnesium</strong></p><p>Supplements or multivitamins containing calcium, iron or magnesium can stop Dovato being absorbed into your body and make it less effective. If you take Dovato with food, you can take supplements or multivitamins containing calcium, iron or magnesium at the same time as Dovato. If you do not take Dovato with food, do not take a supplement or multivitamin containing calcium, iron or magnesium during the 6 hours before you take Dovato, or for at least 2 hours after you take it.</p><ul><li>Talk to your doctor for further advice on taking supplements or multivitamins containing calcium, iron or magnesium with Dovato.</li></ul><p><strong>If you take more Dovato than you should</strong></p><p>If you take too many tablets of Dovato contact your doctor or pharmacist for advice. If possible, show them the Dovato pack.</p><p><strong>If you forget to take Dovato</strong></p><p>If you miss a dose, take it as soon as you remember. But if your next dose is due within 4 hours, skip the dose you missed and take the next one at the usual time. Then continue your treatment as before.</p><ul><li>Do not take a double dose to make up for a forgotten dose.</li></ul><p><strong>Don’t stop taking Dovato without advice from your doctor</strong></p><p>Take Dovato for as long as your doctor recommends. Don’t stop unless your doctor tells you to. Stopping Dovato can affect your health and how future treatment works.</p><p>If you have any further questions on the use of this medicine, ask your doctor or pharmacist.</p></div></samplePreprocessTag></samplePreprocessTag3>"}},{"title":"4. Possible side effects","code":{"coding":[{"system":"https://spor.ema.europa.eu/rmswi/","code":"100000155538"}],"text":"4. Possible side effects"},"text":{"status":"additional","div":"<samplePreprocessTag><samplePreprocessTag3><div xmlns=\"http://www.w3.org/1999/xhtml\"><p>Like all medicines, this medicine can cause side effects, although not everybody gets them, so it is very important to talk to your doctor about any changes in your health.</p><p><strong>Allergic reactions</strong></p><p>Dovato contains dolutegravir. Dolutegravir can cause a serious allergic reaction known as a hypersensitivity reaction. This is an uncommon reaction (may affect up to 1 in 100 people) in people taking dolutegravir. If you get any of the following symptoms:</p><ul><li>skin rash</li><li>a high temperature (fever)</li><li>lack of energy (fatigue)</li><li>swelling, sometimes of the face or mouth (angioedema), causing difficulty in breathing</li><li>muscle or joint aches.</li><li>See a doctor straight away. Your doctor may decide to carry out tests to check your liver, kidneys or blood, and may tell you to stop taking Dovato.</li></ul><p><strong>Very common side effects</strong></p><p>These may affect more than 1 in 10 people:</p><ul><li>headache</li><li>diarrhoea</li><li>feeling sick (nausea).</li></ul><p><strong>Common side effects</strong></p><p>These may affect up to 1 in 10 people:</p><ul><li>depression (feelings of deep sadness and unworthiness)</li><li>rash</li><li>itching (pruritus)</li><li>being sick (vomiting)</li><li>stomach (abdominal) pain or discomfort</li><li>weight gain</li><li>wind (flatulence)</li><li>dizziness</li><li>feeling drowsy</li><li>difficulty sleeping (insomnia)</li><li>abnormal dreams</li><li>lack of energy (fatigue)</li><li>hair loss</li><li>anxiety</li><li>joint pain</li><li>muscle pain.</li></ul><p>Common side effects that may show up in blood tests are:</p><ul><li>increase in the level of liver enzymes (aminotransferases)</li><li>increase in the level of enzymes produced in the muscles (creatine phosphokinase).</li></ul><p><strong>Uncommon side effects</strong></p><p>These may affect up to 1 in 100 people:</p><ul><li>inflammation of the liver (hepatitis)</li><li>suicidal attempt (particularly in patients who have had depression or mental health problems before)</li><li>suicidal thoughts (particularly in patients who have had depression or mental health problems before).</li><li>panic attack</li></ul><p>Uncommon side effects that may show up in blood tests are:</p><ul><li>a decreased number of cells involved in blood clotting (thrombocytopenia)</li><li>a low red blood cell count (anaemia) or low white blood cell count (neutropenia).</li></ul><p><strong>Rare side effects</strong></p><p>These may affect up to 1 in 1000 people:</p><ul><li>liver failure (signs may include yellowing of the skin and the whites of the eyes or unusually dark urine)</li><li>swelling, sometimes of the face or mouth (angioedema), causing difficulty in breathing</li><li>inflammation of the pancreas (pancreatitis)</li><li>breakdown of muscle tissue.</li><li>suicide (particularly in patients who have had depression or mental health problems before)</li><li>Tell your doctor immediately if you experience any mental health problems (see also other mental health problems above).</li></ul><p>Rare side effects that may show up in blood tests are:</p><ul><li>increase in bilirubin (a test of liver function)</li><li>increase in an enzyme called amylase.</li></ul><p>Very rare side effects These may affect up to 1 in 10,000 people:</p><ul><li>lactic acidosis (excess lactic acid in the blood)</li><li>numbness, tingly feelings in the skin (pins and needles)</li><li>sensation of weakness in the limbs.</li></ul><p>Very rare side effects that may show up in blood tests are:</p><ul><li>a failure of the bone marrow to produce new red blood cells (pure red cell aplasia).</li></ul><p><strong>Other possible side effects</strong></p><p>People taking combination therapy for HIV may get other side effects.</p><p><strong>Symptoms of infection and inflammation</strong></p><p>People with advanced HIV infection or AIDS have weak immune systems, and are more likely to develop serious infections (opportunistic infections). Such infections may have been “silent” and not detected by the weak immune system before treatment was started. After starting treatment, the immune system becomes stronger, and may attack the infections, which can cause symptoms of infection or inflammation. Symptoms usually include fever, plus some of the following:</p><ul><li>headache</li><li>stomach ache</li><li>difficulty breathing. In rare cases, as the immune system becomes stronger, it can also attack healthy body tissue (autoimmune disorders). The symptoms of autoimmune disorders may develop many months after you start taking medicine to treat your HIV infection. Symptoms may include:</li><li>palpitations (rapid or irregular heartbeat) or tremor</li><li>hyperactivity (excessive restlessness and movement)</li><li>weakness beginning in the hands and feet and moving up towards the trunk of the body. If you get any symptoms of infection or if you notice any of the symptoms above:</li><li>Tell your doctor immediately. Don’t take other medicines for the infection without your doctor’s advice.</li></ul><p><strong>Joint pain, stiffness and bone problems</strong></p><p>Some people taking combination therapy for HIV develop a condition called osteonecrosis. With this condition, parts of the bone tissue are permanently damaged because of reduced blood supply to the bone. People may be more likely to get this condition:</p><ul><li>if they have been taking combination therapy for a long time</li><li>if they are also taking anti-inflammatory medicines called corticosteroids</li><li>if they drink alcohol</li><li>if their immune systems are very weak</li><li>if they are overweight.</li></ul><p><strong>Signs of osteonecrosis include:</strong></p><ul><li>stiffness in the joints</li><li>aches and pains in the joints (especially in the hip, knee or shoulder)</li><li>difficulty moving. If you notice any of these symptoms:</li><li><strong>Tell your doctor.</strong></li></ul><p><strong>Weight, blood lipid and blood glucose effects:</strong></p><p>During HIV therapy there may be an increase in weight and in levels of blood lipids and glucose. This is partly linked to restored health and lifestyle, and sometimes to the HIV medicines themselves. Your doctor will test for these changes.</p><p><strong>Reporting of side effects</strong></p><p>If you get any side effects, talk to your doctor or pharmacist. This includes any possible side effects not listed in this leaflet. You can also report side effects directly via the national reporting system listed in Appendix V. By reporting side effects you can help provide more information on the safety of this medicine.</p></div></samplePreprocessTag></samplePreprocessTag3>"}},{"title":"5. How to store Dovato 50 mg/300 mg film-coated tablets","code":{"coding":[{"system":"https://spor.ema.europa.eu/rmswi/","code":"100000155538"}],"text":"5. How to store Dovato 50 mg/300 mg film-coated tablets"},"text":{"status":"additional","div":"<samplePreprocessTag><samplePreprocessTag3><div xmlns=\"http://www.w3.org/1999/xhtml\"><p>Keep this medicine out of the sight and reach of children.</p><p>Do not use this medicine after the expiry date which is stated on the carton and bottle after EXP. The expiry date refers to the last day of that month.</p><p>This medicine does not require any special storage conditions.</p><p>Do not throw away any medicines via wastewater or household waste. Ask your pharmacist how to throw away medicines you no longer use. These measures will help protect the environment.</p></div></samplePreprocessTag></samplePreprocessTag3>"}},{"title":"6. 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2023-09-14 16:03:20.150  INFO 33598 --- [nio-8080-exec-2] okhttp3.OkHttpClient                     : <-- END HTTP (41685-byte body)
2023-09-14 16:03:20.165  INFO 33598 --- [nio-8080-exec-2] ca.uhn.fhir.context.FhirContext          : Creating new FHIR context for FHIR version [R5]
2023-09-14 16:03:20.392 ERROR 33598 --- [nio-8080-exec-2] c.u.f.r.s.i.ExceptionHandlingInterceptor : Failure during REST processing: ca.uhn.fhir.parser.DataFormatException: HAPI-1755: String does not appear to be valid XML/XHTML (error is "ParseError at [row,col]:[1,835]
Message: The element type "samplePreprocessTag3" must be terminated by the matching end-tag "</samplePreprocessTag3>"."): <samplePreprocessTag xmlns="http://www.w3.org/1999/xhtml"><samplePreprocessTag3><div xmlns="http://www.w3.org/1999/xhtml"><p><strong>Dovato 50 mg/300 mg film-coated tablets</strong></p><p><em>dolutegravir/lamivudine</em></p><p><strong>Read all of this leaflet carefully before you start taking this medicine because it contains important information for you.</strong></p><ul><li>Keep this leaflet. You may need to read it again.</li><li>If you have any further questions, ask your doctor, or pharmacist.</li><li>This medicine has been prescribed for you only. Do not pass it on to others. It may harm them, even if their signs of illness are the same as yours.</li><li>If you get any side effects, talk to your doctor, or pharmacist. This includes any possible side effects not listed in this leaflet. See section 4.</li></ul></div></samplePreprocessTag></samplePreprocessTag3>
jkiddo commented 1 year ago

Which sums down to this:

<samplePreprocessTag xmlns="http://www.w3.org/1999/xhtml">
    <samplePreprocessTag3>
        <div xmlns="http://www.w3.org/1999/xhtml">
            <p><strong>Dovato 50 mg/300 mg film-coated tablets</strong></p>
            <p><em>dolutegravir/lamivudine</em></p>
            <p><strong>Read all of this leaflet carefully before you start taking this medicine because it contains
                    important information for you.</strong></p>
            <ul>
                <li>Keep this leaflet. You may need to read it again.</li>
                <li>If you have any further questions, ask your doctor, or pharmacist.</li>
                <li>This medicine has been prescribed for you only. Do not pass it on to others. It may harm them, even
                    if their signs of illness are the same as yours.</li>
                <li>If you get any side effects, talk to your doctor, or pharmacist. This includes any possible side
                    effects not listed in this leaflet. See section 4.</li>
            </ul>
        </div>
</samplePreprocessTag>
</samplePreprocessTag3>

-which isn't correctly terminated

10alejospain commented 1 year ago

That was a example pre proccesing tool that. Using only the manual preproccesing should work perfectly. By applying all of them you'll always find errors during the developing stages. Same thing in the near future one we deliver the automatic proprocessor.

What kind of change did you make to solve the ES/EN ePI problem? Just to get track of the changes.

jkiddo commented 1 year ago

I corrected the identifiers and the languages on the Document bundles. Ideally, this should be done in the IG (FYI @joofio )

jkiddo commented 1 year ago

@10alejospain as a consumer of the service I have no idea of what kind of processing you have applied - and I shouldn't be aware of any such processing. I simply used the reference which you instructucted me to use - and that reference contains errors as it isn't valid XML.

jkiddo commented 1 year ago

Corrections are here: https://github.com/hl7-eu/gravitate-health/commit/2b28c08b3cbddbad41c5b69f4bf274b954da31f3 and https://github.com/hl7-eu/gravitate-health/commit/4ff007fcce4f1f409ccb0057a2b69fa80921f229

jkiddo commented 1 year ago

@10alejospain regardless of the fixes you still have an issue to fix here.

10alejospain commented 1 year ago

Which sums down to this:

<samplePreprocessTag xmlns="http://www.w3.org/1999/xhtml">
    <samplePreprocessTag3>
        <div xmlns="http://www.w3.org/1999/xhtml">
            <p><strong>Dovato 50 mg/300 mg film-coated tablets</strong></p>
            <p><em>dolutegravir/lamivudine</em></p>
            <p><strong>Read all of this leaflet carefully before you start taking this medicine because it contains
                    important information for you.</strong></p>
            <ul>
                <li>Keep this leaflet. You may need to read it again.</li>
                <li>If you have any further questions, ask your doctor, or pharmacist.</li>
                <li>This medicine has been prescribed for you only. Do not pass it on to others. It may harm them, even
                    if their signs of illness are the same as yours.</li>
                <li>If you get any side effects, talk to your doctor, or pharmacist. This includes any possible side
                    effects not listed in this leaflet. See section 4.</li>
            </ul>
        </div>
</samplePreprocessTag>
</samplePreprocessTag3>

-which isn't correctly terminated

This error should be solved rn.

aalonsolopez commented 1 year ago

Now we also have error messages properly working #12