GreenleafLab / ArchR

ArchR : Analysis of Regulatory Chromatin in R (www.ArchRProject.com)
MIT License
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Merging or Combining multiple ArchRProject Objects #2085

Open qdong2023 opened 11 months ago

qdong2023 commented 11 months ago

Hello ArchR developers,

I have several ArchRProject objects that require merging. These ArchR objects originate from distinct batches of arrow files and experiments from 10x multiome kits. It's important to note that I've already conducted batch correction for their multiomic RNA datasets, eliminating the need for additional integration techniques like harmony in ArchR. I'm seeking guidance on the most straightforward approach to combine or merge these multiple ArchR objects. Should I directly merge them, or would it be more prudent to import all arrow files and reconstruct a singular ArchRProject object? Any suggestions on the best course of action would be immensely appreciated!

Thanks!

rcorces commented 11 months ago

Hi @qdong2023! Thanks for using ArchR! Please make sure that your post belongs in the Issues section. Only bugs and error reports belong in the Issues section. Usage questions and feature requests should be posted in the Discussions section, not in Issues.
It is worth noting that there are very few actual bugs in ArchR. If you are getting an error, it is probably something specific to your dataset, usage, or computational environment, all of which are extremely challenging to troubleshoot. As such, we require reproducible examples (preferably using the tutorial dataset) from users who want assistance. If you cannot reproduce your error, we will not be able to help. Before going through the work of making a reproducible example, search the previous Issues, Discussions, function definitions, or the ArchR manual and you will likely find the answers you are looking for. If your post does not contain a reproducible example, it is unlikely to receive a response.
In addition to a reproducible example, you must do the following things before we help you, unless your original post already contained this information: 1. If you've encountered an error, have you already searched previous Issues to make sure that this hasn't already been solved? 2. Did you post your log file? If not, add it now. 3.__ Remove any screenshots that contain text and instead copy and paste the text using markdown's codeblock syntax (three consecutive backticks). You can do this by editing your original post.