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GuoBioinfoLab / TCellSI

The First Innovative Tool to Comprehensively Assess T Cell States
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How to process result from TCellSI::TCSS_Calculate? #2

Open Frank9938 opened 2 weeks ago

Frank9938 commented 2 weeks ago

Hi, I'm writing to ask how to process result calculated by function _TCSSCalculate.

I noticed that sum of each T cell state score in each sample is not equal to 1. It seems that the total score of each T cell state in each sample is influenced by T cell abundance. It's suitable to normalize the result by dividing every T cell state score by total T cell state score?

Looking forward to your reply. Lots of thanks.

VyvyanYjm commented 1 week ago

Hi, I'm writing to ask how to process result calculated by function _TCSSCalculate.

I noticed that sum of each T cell state score in each sample is not equal to 1. It seems that the total score of each T cell state in each sample is influenced by T cell abundance. It's suitable to normalize the result by dividing every T cell state score by total T cell state score?

Looking forward to your reply. Lots of thanks.

It is ok to perform this normalization.

VyvyanYjm commented 1 week ago

Hi, I'm writing to ask how to process result calculated by function _TCSSCalculate.

I noticed that sum of each T cell state score in each sample is not equal to 1. It seems that the total score of each T cell state in each sample is influenced by T cell abundance. It's suitable to normalize the result by dividing every T cell state score by total T cell state score?

Looking forward to your reply. Lots of thanks.

If there are further questions to ask, you can add my wechat: Y1390473501, sometimes I can not see the news on this in time.

Frank9938 commented 1 day ago

Thank you very much! I might contact you further if needed