HKU-BAL / Clair3

Clair3 - Symphonizing pileup and full-alignment for high-performance long-read variant calling
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Why doesn't clair3_c_impl.sh have step 5? #243

Closed oranges7 closed 1 year ago

oranges7 commented 1 year ago

Why does clair3_c_impl.sh not need to generate phase_bam files?

zhengzhenxian commented 1 year ago

@oranges7,

We have integrated the whatshap haptagging functionality into the full-alignment submodule implemented in c implement. In this implementation, all reads are haptagged during the read parsing, eliminating the need for generating intermediate phased BAM files. This optimization significantly reduces the disk space usage.

oranges7 commented 1 year ago

I see. Thank you very much for your quick reply.