SILAC as a feature detection method

HUPO-PSI / psi-mi-CV

Molecular Interactions Controll Vocabulary

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SILAC as a feature detection method #301

Closed noedelta closed 8 years ago

noedelta commented 12 years ago

SILAC (Stable Isotope Labeling by Amino acids in Cell culture) can be used to detect features (typically PTMs) required for a given interaction - see, for example PMID: 2223140 The method is different then mass detection of residue modification (ID: MI:0068) as the modified protein is not the one subjected to MS; rather, SILAC methodology is used to compare the effect of PTM presence/absence on binding of the isotopically labeled preys

Reported by: lukasz99

noedelta commented 11 years ago

MI:1234

Original comment by: orchard

noedelta commented 11 years ago

status: open --> closed

Original comment by: orchard