HUPO-PSI / psi-mi-CV

Molecular Interactions Controll Vocabulary
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Two more fluorescent labels: Acrylodan, Pyrene #317

Closed noedelta closed 8 years ago

noedelta commented 12 years ago

These are needed to annotate PMID:22723742

Reported by: lukasz99

noedelta commented 12 years ago

MI:1259

Original comment by: orchard

noedelta commented 12 years ago

Original comment by: orchard

noedelta commented 12 years ago

acrylodan - MI:1259. I've entered pyrene as pyrene derivaitves (MI:1260) as pyrene itself does not appear to be fluorescent.

Original comment by: orchard

noedelta commented 12 years ago

pyrene on it's own seems to be fluorescent - functional groups are added just to get it attached to the molecule of interest, like here: http://www.mdpi.com/1420-3049/16/9/7909/pdf

Fluorescein is listed as 'fluorescein label' (MI:0939) with different reactivity-related derivatives listed as its children - shouldn't pyrene be treated the same way ? Or do we consider a florescent label modified by adding labeling-related functional groups as derivatives ?

Original comment by: lukasz99