defined set

[noedelta]

Two or more physicalEntities, grouped to denote interchangeable function. Thus the addition of a single nucleotide residue during RNA transcription could be annotated with the definedSet NTP [nucleoplasm] (members ATP, CTP, GTP, and UTP) as input. This is useful to prevent combinatorial explosion. Any kind of physicalEntity can belong to a definedSet. Example: Cdk4/6 [nucleoplasm], with Cdk4 and Cdk6 as hasMember values. This set is used to annotate the formation of a single complex, "Cyclin D:Cdk4/6 [nucleoplasm]", which in turn is an input entity for a single Reactome event, "Phosphorylation of Cyclin D:Cdk4/6 complexes". ([28]) The creation of single events that have entity sets as inputs, outputs, and the physicalEntity value of catalystActivities is preferred over the creation of eventSets in which each member event involves a different member of an isozyme family as its catalyst.

as child_of interactorType = set

from Reactome data Model: http://wiki.reactome.org/index.php/Glossary\_Data\_Model

Reported by: bmeldal

[noedelta]

MI:1307

Original comment by: orchard

[noedelta]

• status: open --> closed
• Group: -->

Original comment by: orchard