SUMMARY: ELSI has forwarded an email asking whether “there exist formal standards that represent different types of research studies including cohort, clinical cohort, population cohort, case only, case-control, biobank, clinical study, clinical trial, registry, and so on?
Some clarifying questions from my side
can dct:type be used to represent the type of various domains of dataset?
My answer is No,dct:type should be used for representing catalogue and dataset and their specific domains. it is not meant to be used at the research project level.
Do the above mentioned type of studies can all be categorized as studies?
for example It seems that biobank is a service (catalogue) of various datasets having including various studies and specific types of collection, while for example clinical study is broader term defining a type of research project. So i assume that biobank could contain clinical studies?
I see that we have introduced hri:Study that is linked to the dct:dataset shall we further develop this in terms of its structure and controlled vocabularies to define Study?
Do you know of any standards that defines a structure and vocabularies for research Studies? I found the the generic ones:
• The Study Design Ontology (SDO):
o Focused on the design of scientific studies, SDO captures different study design types and their associated attributes.
It can be useful if we want to represent and classify the design aspect of your studies.
Link to Study Design Ontology
• The Ontology for Biomedical Investigations (OBI):
o A comprehensive ontology for biomedical investigations.
It provides classes and relations to represent all aspects of the study, from the design, protocols, instrumentation, materials, data generated, and more.
Link to OBI
• Clinical Trial Ontology (CTO):
o Specifically focused on clinical trials, which you mentioned as one of your study types.
It categorizes and relates different aspects of clinical trials.
Link to Clinical Trial Ontology
• Experimental Factor Ontology (EFO):
o It is often used in genomics and related areas.
Besides covering experimental factors, EFO also encompasses study designs and other related aspects.
Link to EFO
"Ons team heeft afgelopen tijd een metadata catalogus ontwikkeld voor cohorten en biobanken. Eén van de metadatavelden betreft het type databron en we worstelen wat met de definities van de verschillende types. Hieronder een overzicht van de types. Weten jullie of er standaard definities voor deze types zijn die jullie kunnen adviseren?
Clinical cohort: A group of individuals with a common condition or characteristic who are followed over time to study the natural history or treatment of the condition.
Population cohort: A group of individuals selected from a defined population or community who are followed over time to investigate the natural history and risk factors of a disease or health outcome.
Case-control: A type of study that compares individuals with a disease (cases) to individuals without the disease (controls).
Case only: A type of study that includes only individuals with the disease of interest.
Birth cohort: A group of individuals born during a particular time period or in a particular geographic area
Registry: A database that collects and stores information about individuals with a particular disease or condition.
Biobank: A resource with biological samples and associated data from individuals.
Clinical study: A research project that investigates a particular topic or question.
Clinical trial: A study that investigates the safety and effectiveness of new medical treatments or interventions.
Other type: Another type of cohort."
brunasv
commented
6 months ago
Hello Bruna and Jeroen,
Need a consultation on the following email.
SUMMARY: ELSI has forwarded an email asking whether “there exist formal standards that represent different types of research studies including cohort, clinical cohort, population cohort, case only, case-control, biobank, clinical study, clinical trial, registry, and so on? Some clarifying questions from my side
"Ons team heeft afgelopen tijd een metadata catalogus ontwikkeld voor cohorten en biobanken. Eén van de metadatavelden betreft het type databron en we worstelen wat met de definities van de verschillende types. Hieronder een overzicht van de types. Weten jullie of er standaard definities voor deze types zijn die jullie kunnen adviseren?
Clinical cohort: A group of individuals with a common condition or characteristic who are followed over time to study the natural history or treatment of the condition. Population cohort: A group of individuals selected from a defined population or community who are followed over time to investigate the natural history and risk factors of a disease or health outcome. Case-control: A type of study that compares individuals with a disease (cases) to individuals without the disease (controls). Case only: A type of study that includes only individuals with the disease of interest. Birth cohort: A group of individuals born during a particular time period or in a particular geographic area Registry: A database that collects and stores information about individuals with a particular disease or condition. Biobank: A resource with biological samples and associated data from individuals. Clinical study: A research project that investigates a particular topic or question. Clinical trial: A study that investigates the safety and effectiveness of new medical treatments or interventions. Other type: Another type of cohort."