You can’t clear the first puzzle of the Boomsday Project last level (survival with Dr.Boom). His hero power will randomly activate when playing your cards (try it by yourself).
Acknowledged by Blizzard:
Thanks for the report! I confirmed that it does happen after refreshing your mana and playing the next card. We will have this looked at.
https://www.reddit.com/r/hearthstone/comments/bwqgfc/bug_dr_boom_survival_1_makes_it_impossible_to/
The puzzle quest triggers, the hero power fires, your hero takes 40 damage, and the puzzle resets.
https://us.forums.blizzard.com/en/hearthstone/t/boomsday-project-adventure-unclearable/7339
Acknowledged by Blizzard: