R implementation of GLIPH (Grouping of Lymphocyte Interactions by Paratope Hotspots), an algorithm developed by Glanville et al to identify specificity groups in the T cell receptor repertoire based on local (motif sharing) and global (hamming distance) similarities.
Thank you for the useful code/package, super useful.
I ran successfully the software and plot_network for 6 subjects from 3 different antigens.
I wanted to summarize which antigen are specific/unique for clusters, which clusters are shared across all antigens etc.
Do you have code than can summarize and plot differences in various metrics like clusters and members in each clusters across Antigens you can share ?
Thank you for the useful code/package, super useful.
I ran successfully the software and plot_network for 6 subjects from 3 different antigens.
I wanted to summarize which antigen are specific/unique for clusters, which clusters are shared across all antigens etc. Do you have code than can summarize and plot differences in various metrics like clusters and members in each clusters across Antigens you can share ?
Thanks again for this great resource