HingeAssembler / HINGE

Software accompanying "HINGE: Long-Read Assembly Achieves Optimal Repeat Resolution"
http://genome.cshlp.org/content/27/5/747.full.pdf+html?sid=39918b0d-7a7d-4a12-b720-9238834902fd
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Question: `clip` vc `clip-nanopore`? #119

Open spock opened 7 years ago

spock commented 7 years ago

I have a dazzler database with a combination of PacBio and Nanopore reads. Which of the clip options is more suitable in this case? Thank you in advance :)

govinda-kamath commented 7 years ago

I'd suggest clip-nanopore as the nanopore reads have more correlated errors, which could lead to mis-assemblies.

We've never bench-marked on any such data-sets though. Are there any publicly available data-sets with a combination of pacbio and nanopore reads?

spock commented 7 years ago

Thanks a lot for a quick response! I'll try clip-nanopore.

This dataset is, unfortunately, not public. If I have enough time, I may also test clip on this dataset, and see which one seems to work better (there is no reference genome, but we know the approximate genome size).