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HingeAssembler / HINGE

Software accompanying "HINGE: Long-Read Assembly Achieves Optimal Repeat Resolution"
http://genome.cshlp.org/content/27/5/747.full.pdf+html?sid=39918b0d-7a7d-4a12-b720-9238834902fd
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Filter multiple alignment in a single read #126

Closed BHZ-BER closed 6 years ago

BHZ-BER commented 6 years ago

Previously all the local alignments from DAligner are taken for consensus. A better way could be only allowing one alignment for each read in consensus. Here I'm only using the longest alignment for each read in consensus step. This has led to a ~0.3% accuracy increase in ecoli assembly.

ilanshom commented 6 years ago

Thanks, Banghua! That's a nice improvement.

govinda-kamath commented 6 years ago

Thanks @13aeon. This looks great!