Template 8

[mariebeslay]

It seeems that the denominator include all pregnancies, including those without MS, and even more. The denominator during the entire period is 149,399 whereas 141,539 are included according to template 1

[DavideMessinaARS]

In attachment a newer step 09_T3_20.zip to test. This should retain only pregnancies with MS

[mariebeslay]

Thanks it works.

Here are new issues : The denominator in 2005-2019 is 125 instead of the 123 pregnancies with MS (we have 123 in Template 1). Some lines are in double : 2005-2019 (one always contains 0 exposed preg)

For exposure before pregnancy (column_identifier=pre_1 to pre_4): I can't find the definition of pre_1 to pre_4. pre_1 is the only containing exposed cases so I assume this is the 3 months before pregnancy. But the same results should be obseved for 12 months before pregnancy

For exposure during T1 / year : still wrong denominator for 2005-2019 + in 2015 I have 2 more pregnancies exposed to glat_acetate than you have.

For exposure during T2 and T3 / year : we have the same exposure but the denominators do not seem correct because they are similar to denominator for T1, but we have some pregnancies ending in T1/T2 that should not be in the denominator.

Stratification / age : we have different results

Should we meet ?

[DavideMessinaARS]

Should we meet ?

ok

[mariebeslay]

I have an exposure after pregnancy to Interferon_beta_1a in 2014 (25-29 age group) but we do not have data after pregnancy in EFEMERIS, and I do not see a pregnancy starting <3 months after the end of a previous one that could explain this exposure

[DavideMessinaARS]

Are you available tomorrow afternoon for a call?

[mariebeslay]

Yes, what time ?

[DavideMessinaARS]

I'm not sure. At 12 I should be the most free. Now that I think about it in the afternoon I may be traveling

[mariebeslay]

Ok for 12 ! And if you are available before, let me know