Illumina / manta

Structural variant and indel caller for mapped sequencing data
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several sample have a signaficant higher SV numbers among groups #232

Open wanhui5867 opened 4 years ago

wanhui5867 commented 4 years ago

Hi,

I used manta to analysis a group of samples, all of them are run successfully without error. While when I summary the SV number of all samples, it looks strange to some samples that have a really higher SVs number (100-300) than others (<50) (See below figure). I checked those outlier samples' sequencing alignment and other mutational (SNVs, CNVs) results, but they have no big difference with other samples. All the samples are running with the sample parameters. image

Does anyone have the same problem? Is the situation normal, if not how to deal with it?