Illumina / manta

Structural variant and indel caller for mapped sequencing data
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Increase the max allowed base Q score from 70 to 93 #284

Open clintval opened 2 years ago

clintval commented 2 years ago

There are now error-corrected NGS technologies that can produce base quality scores Q60+. To make those technologies compatible with the Manta program, we need to increase the maximum allowed base quality score. A score of 93 is the maximum defined in the SAM spec v1 §4.2.3:

Base qualities are stored as bytes in the range [0, 93], without any +33 conversion to printable ASCII.

This is also the maximum for the HTSJDK project.