I am interested in detecting de novo mutations on my WGS trio samples. In your manual, you mentioned that the best choice of additional quality score de novo (DQ) threshold will depend on the application and the recommended default threshold is 7.
Would it be possible to give more detail or an example of the correlation between one or more applications and the DQ value?
On the other hand,, I would like to know the recommended value (= 7) according to what criteria?
Dear colleagues,
I am interested in detecting de novo mutations on my WGS trio samples. In your manual, you mentioned that the best choice of additional quality score de novo (DQ) threshold will depend on the application and the recommended default threshold is 7.
Would it be possible to give more detail or an example of the correlation between one or more applications and the DQ value? On the other hand,, I would like to know the recommended value (= 7) according to what criteria?
Thanks, Talo