Closed AndrewCRMartin closed 2 years ago
I separated out the second issue
I see the issue. This is because I initially did not allow VHH domains to be paired with another to demonstrate that they are single domain Fv fragments. I can have this changed so it allows a disulphide between two VHH domains.
That's great - but the VHH still now renders as a VH instead of a VHH :)
Sorted
It still renders as a VH instead of a VHH for me!
VHH.a(1:5){1}-H(2:6){2}-CH2(3:7)-CH3(4:8)|VHH.a(5:1){1}-H(6:2){2}-CH2(7:3)-CH3(8:4)
Compared with
VHH.a(1)-H(2:6){3}-CH2(3:7)-CH3(4:8)|VHH.a(5)-H(6:2){3}-CH2(7:3)-CH3(8:4)
This is what I'm getting now. If you use the latest version of the programme, this issue is gone when using the expression I've used here. I've also replaced the Camelid
antibody in the library for this structure
Ah - brilliant - I must have done my git pull
too soon!!!!
Yes, that's probably me responding to your query and then updating the code. I'll do it from the other way around now.
The following renders correctly except that the VHH displays as a VH instead of a VHH: