JamesSweetJones / abYdraw

Input expressions of antibodies in AbML format and output drawings of their shape
GNU General Public License v3.0
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Typical ef- structure renders, but Fc separated #43

Closed AndrewCRMartin closed 1 year ago

AndrewCRMartin commented 1 year ago

ef-xxxxxx structures are protein drugs stabilized by attaching to an Fc (so that the FcRn recycling can be exploited). So this is just an Fc fragment with an other attached to each hinge:

X(1)-H(2:6){2}-CH2(3:7)-CH3(4:8)|X(5)-H(6:2){2}-CH2(7:3)-CH3(8:4)

This does render but the two halves of the Fc are a long way apart. If you then click tidy, it loses the interactions between the Fc halves.

JamesSweetJones commented 1 year ago

Solved in latest push