JamesSweetJones / abYdraw

Input expressions of antibodies in AbML format and output drawings of their shape
GNU General Public License v3.0
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scFv-TCR not bringing the TCR chains together properly #44

Closed AndrewCRMartin closed 2 years ago

AndrewCRMartin commented 2 years ago
VL.a(1:3)-L(2)-VH.a(3:1)-L(4)-VB.a(5:7)-CB*(6:8){1}|VA.a(7:5)-CA*(8:6){1}

This structure is an scFv(VL-VH) fused via a linker to a TCR beta chain. The beta chain region then pais with an alpha chain with the constant domains having an artificial disulphide.

It renders, but the VB-CB is miles away from the VA-CA

JamesSweetJones commented 2 years ago

Solved in latest push