JamesSweetJones / abYdraw

Input expressions of antibodies in AbML format and output drawings of their shape
GNU General Public License v3.0
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Another structure that doesn't render #45

Open AndrewCRMartin opened 2 years ago

AndrewCRMartin commented 2 years ago
X(1)-L(2)-VH.a(3:12)-L(4)-VL.a(5:10)-L(6)-X(7)|X(8)-L(9)-VH.a(10:5)-L(11)-VL.a(12:3)-L(13)-X(14)

This is a crossed scFv (i.e. two scFvs with short linkers such that VH of one interacts with VL of the other) - both having identical sequences and antigens. i.e.

VH.a(1:6)-L(2)-VL.a(3:4)|VH.a(4:3)-L(5)-VL.a(6:1)

which renders fine, but happens to have an X domain on both ends of each chain.

JamesSweetJones commented 2 years ago
Screenshot 2022-09-15 at 10 28 07

It renders now, but having some trouble getting the AbML for it

AndrewCRMartin commented 2 years ago

This is OK, but on the left wouln't it be more logical ifthe X connected to the VLa were at the top and the X connected to the VHa were at the bottom?

A.