RSV epitope content comparison - Githubissues

JianiC / RSV_Epitope

5 stars 2 forks source link

RSV epitope content comparison #6

Open JianiC opened 3 years ago

JianiC commented 3 years ago

Example with RSVB-F

evaluate with vaccine candidates

Screen Shot 2020-11-02 at 4 17 05 PM

Within in subtype , F is very conserved, RSVA_F produce partial protection

JianiC commented 3 years ago

RSVBF T cell content MDS

Screen Shot 2020-11-02 at 4 29 23 PM

number of cluster

Screen Shot 2020-11-02 at 4 22 54 PM

map to ML tree

Screen Shot 2020-11-02 at 4 23 50 PM

against time

Screen Shot 2020-11-02 at 4 23 59 PM

ML genetic distance MDS

Screen Shot 2020-11-02 at 4 28 00 PM

genetic distance across time

Screen Shot 2020-11-02 at 4 28 12 PM

JianiC commented 3 years ago

[ ] Should test RSV-G protein, F is too conserved
[ ] Use the Cluster I defined from my nomenclature system, also simulate the ancestral node for each clade