Jiaxin-Fan
commented
4 years ago Hi Charles,
ASEP is an RNA-seq data-based method and only takes integer value as input for ‘ref’ and ‘total’. I am not quite familiar with DNA methylation. But as long as you think the changings in ratio of ref/total before and after the rounding is similar, then I would say rounding to integer would be a good way to handle the data.
Best, Jiaxin
From: Charles notifications@github.com Reply-To: Jiaxin-Fan/ASEP reply@reply.github.com Date: Wednesday, August 5, 2020 at 3:21 AM To: Jiaxin-Fan/ASEP ASEP@noreply.github.com Cc: Subscribed subscribed@noreply.github.com Subject: [External] [Jiaxin-Fan/ASEP] How to process the float values (#1)
At sometimes, the "ref" column: “the SNP-level allele-specific read counts of the reference allele” contains the float type values, for example, DNA methylation. So, is it practical to run the ASEP software after int(float value)? or do you have any suggestions?
thank you.
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At sometimes, the "ref" column: “the SNP-level allele-specific read counts of the reference allele” contains the float type values, for example, DNA methylation. So, is it practical to run the ASEP software after int(float value)? or do you have any suggestions?
thank you.