Jiaxin-Fan / ASEP

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Apply ASEP to RNA-seq samples of pooled individuals #15

Open Sfeng666 opened 10 months ago

Sfeng666 commented 10 months ago

Hi Jiaxin,

I appreciate that you proposed this exciting approach for unphased data. Also congrats on the publication!

As an open question the may go beyond this specific tool, I wonder if you have thought about the feasibility of identify ASEPs from samples of pooled individuals (e.g., RNA-seq libraries that each contains 100 heterozygous fruit flies). If not feasible, what are the theoretical obstacles?

Thanks, Siyuan