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JinmiaoChenLab / GraphST

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Question for integrating different sources of ST and scRNA-seq data #29

Open Fanyu000 opened 5 months ago

Fanyu000 commented 5 months ago

Hi, I have used ST data from a study, but because of the lack of corresponding scRNA-seq, I have to use my previous scRNA-seq integrated datasets for reference.

By using this method, I get a set of single cell data distribution in ST tissue visualization figures. Do you think this figure can simulate the authentic cell types distribution in tissue?

Thanks :)

longyahui commented 4 months ago

Hi,

Thank you for your question.

GraphST can accurately project scRNA-seq data into ST sample if both data is matched well enough. I am not sure whether the scRNA-seq and ST data you used are matched. Thanks again.

Best regards,
Yahui
Fanyu000 commented 4 months ago

Okay, thanks. I assumed that it can reflect the overall situation because the scRNA-seq integrated data has about 40 samples, while they are not matched samples.

Thanks, Fanyu

longyahui @.***> 于2024年4月22日周一 15:20写道：

Hi,

Thank you for your question.

GraphST can accurately project scRNA-seq data into ST sample if both data is matched well enough. I am not sure whether the scRNA-seq and ST data you used are matched. Thanks again.

Best regards, Yahui

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