KIT-MBS / pycofitness

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Does this only work for single point mutations in proteins? #1

Open danny305 opened 3 months ago

danny305 commented 3 months ago

Is there a way to have this library give me score for double and triple mutants?

3BioCompBio commented 2 months ago

Dear Danny, thank you for your interest in pycofitness. It is not possible at the moment but we could implement it. I will let you know if we decide to do it. Alternatively you could consider that there is no epistasis between mutations and just some the contributions of each individual mutation even if it is an approximation.