Chromosome varying effects

Kevin-Haigis-Lab / speclet

A Bayesian hierarchical model to discover tissue-specific cancer driver genes and synthetic lethal interactions from CRISPR/Cas9 LoF screens.

GNU General Public License v3.0

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Chromosome varying effects #183

Closed jhrcook closed 2 years ago

jhrcook commented 2 years ago

Add another set of varying effects for each chromosome: varying intercept and varying slope with CN. This could be a completely new pair of variables or nested within cell line.