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KlementineJBS / USYD_PhD_ELN

This repository forms the electronic laboratory notebook (ELN)for Klementine Burrell-Sander's PhD's
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KBS39-2 - NBS reaction on KBS37 (large scale) #128

Closed KlementineJBS closed 9 months ago

KlementineJBS commented 10 months ago

Link to HIRAC and master page.

HIRAC NBS reaction Breaking Good.docx

Reaction scheme

KBS39 - NBS reaction on KBS37

Outcome

925.3 mg of which 418.1 mg is calculated to be product, giving conversion rate of 45% and yield of 35%

KlementineJBS commented 10 months ago

27.08.23

  1. Dissolved SM (811.3 mg, 4.74 mmol) in MeCN
  2. Added tosic acid (1.224 g, 7.11 mmol, 1.5 equiv.) and NBS (1.0147 g, 5.69 mmol, 1.2 equiv.)
  3. Left stirring
KlementineJBS commented 10 months ago

Empty vial: 15.6874 Full vial: 16.6127 Mass: 925.3 mg of which 418.1 mg is calculated to be product, giving conversion rate of 45% and yield of 35%

KlementineJBS commented 10 months ago

H NMR

KBS39-2 cr.pdf KBS39-2 cr_1.zip