KlugerLab / ALRA

Imputation method for scRNA-seq based on low-rank approximation
MIT License
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Input format (genes as rows?) #9

Closed anacarolinaleote closed 4 years ago

anacarolinaleote commented 4 years ago

Thank you for the interesting approach to dropout imputation! I know it's documented, but different parts of the documentation say different things: should the input matrix have genes as rows and cells as columns or the other way around? Thanks!

JunZhao1990 commented 4 years ago

Thank you for your interest in ALRA. If you use the function alra() directly, the input matrix should have cells in rows and genes in columns. The function alraSeurat2() will take a Seurat v2 object directly.