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KoslickiLab / fmh-funprofiler

A functional profiler for metagenomes using FracMinHash
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More information on the KO Abundance #8

Closed doy-pin closed 3 months ago

doy-pin commented 3 months ago

Hi,

Can you confirm if the values are relative abundance and is there a way to convert them into copies per million?

mahmudhera commented 3 months ago

Yes, the values are relative abundances, they should sum to 1.0.

I do not think there is any direct way to convert the values into a gross copy number. Doing so requires us to be able to definitively say that a KO is present x number of times, whereas, in the metagenome data, pieces of the genes in the KOs are present in a scattered (and perhaps messy) manner.