Lattice-Automation / seqfold

nucleic acid folding
MIT License
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seqfold not finding folding at certain sequence lengths #20

Open tuspjo opened 2 weeks ago

tuspjo commented 2 weeks ago

Hello, Thank you for making and maintaining this tool. I'm trying to figure out the best folding for a sequence of unknown length, so I'm trying all reasonable sequence lengths 2-100 nt the issue is that for certain lengths, seqfold is unable to find more than a single paired base, even though there are plenty of hairpins in the sequence. in the attached image, each line is the dotbrackt view of one seqfold run, each with +1nt of the same sequence image

do you know what this software behaviour could be caused by?

Best

Tue