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LieberInstitute / Visium_SPG_AD

Visium SPG AD project (n = 10) using Visium Spatial Proteogenomics (Visium-SPG) on dissections from the inferior temporal cortex (ITC) from Alzheimer's disease cases and controls.
https://research.libd.org/Visium_SPG_AD
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Compare pathology spots (7 categories) vs bayespace k = 28 in a heatmap #50

Closed lcolladotor closed 1 year ago

lcolladotor commented 2 years ago

We anticipate that it'll show that spatial clustering methods like BayesSpace can't find the pathology spots just using gene expression by itself. That's why you need the IF part. Yet, there is still some gene expression differences as we can find DE genes across the pathology groups.

shkwon17 commented 1 year ago

This is not covered within the current manuscript but could be revisited in the future.