Visium SPG AD project (n = 10) using Visium Spatial Proteogenomics (Visium-SPG) on dissections from the inferior temporal cortex (ITC) from Alzheimer's disease cases and controls.
Generate Volcano plots for the following 7 categories:
1) Ab
2) n_Ab
3) pTau
4) n_pT
5) Both
6) n_Bo
7) none
Genes that need to be highlighted
1) for the Ab category: UBE2A, PSMC4, IDI1, NINJ1 (FDR <0.1)
2) for the n_Ab category: C3, PPP3CA, UCHL1, SST (FDR <0.1)
-Ab and n_Ab will be on the main figure, while the other 5 will be on the supplementary figure.
Generate Volcano plots for the following 7 categories: 1) Ab 2) n_Ab 3) pTau 4) n_pT 5) Both 6) n_Bo 7) none
Genes that need to be highlighted 1) for the Ab category: UBE2A, PSMC4, IDI1, NINJ1 (FDR <0.1) 2) for the n_Ab category: C3, PPP3CA, UCHL1, SST (FDR <0.1)
-Ab and n_Ab will be on the main figure, while the other 5 will be on the supplementary figure.
-relevant mockup image