LieberInstitute / spatialDLPFC

spatialDLPFC project involving Visium (n = 30), Visium SPG (n = 4) and snRNA-seq (n = 19) samples
http://research.libd.org/spatialDLPFC/
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re-make pseudobulked objects #102

Closed abspangler13 closed 2 years ago

abspangler13 commented 2 years ago

resolve this: https://jhu-genomics.slack.com/archives/CR9NYA0BF/p1652035798464949. need to go back change the FilterByExpr use in pseudobulking code. look at latest visium_IF_AD. switch column names from low to high so it's self-explanatory. make sure to use group argument in order to keep more genes. need to make different pseudobulked objects for each differential expression analysis. group by region for region DE analysis.