LungCellAtlas / HLCA

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how is the CO annotation generated? #13

Closed YOU-k closed 6 months ago

YOU-k commented 10 months ago

Thanks for providing such a useful resource summarizing expression profiles from lungs. I checked the labels provided on cellxgene, there are several sets of labels. I understand how the author provided labels are generated according to the method section in the paper. but how are the CO labels in the standard categories generated? I noticed there can be inconsistency between any level of the annotation compared to it. Cheers, Yue

LisaSikkema commented 9 months ago

Hi Yue,

Thank you for your kind words! You can find the exact mapping we used to go from the final annotations to the cell-ontology-based ones in the reproducibility GitHub, here: https://github.com/LungCellAtlas/HLCA_reproducibility/blob/main/supporting_files/metadata_harmonization/cell_type_mapping_to_cellontology.csv Let me know if that answers your question or if you need anything else!

YOU-k commented 9 months ago

Thanks, Lisa, that's very helpful.