search

MBoemo / DNAscent

Software for detecting regions of BrdU and EdU incorporation in Oxford Nanopore reads.
https://www.boemogroup.org/
GNU General Public License v3.0
26 stars 13 forks source link

Calling other base analogs? #21

Closed altemose closed 2 years ago

altemose commented 2 years ago

Hello and thanks for the excellent work on this. Can DNAscent v2 detect other base analogs like EdU with any accuracy out of the box? (Not multiple analogs simultaneously, just EdU instead of BrdU). If not, is it possible for the user to retrain the residual neural net on control samples?

MBoemo commented 2 years ago

Replied in DM, closing.

najohink commented 2 years ago

I too was wondering how DNAscent would perform out of the box on other dU analogues. Any insight or suggestions would be appreciated. Thanks!

MBoemo commented 2 years ago

At the moment, only BrdU and EdU are supported, but we're working on a few other possibilities.