ME-ICA / tedana

TE-dependent analysis of multi-echo fMRI
https://tedana.readthedocs.io
GNU Lesser General Public License v2.1
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Add functionality for dependency between echoes #806

Open handwerkerd opened 2 years ago

handwerkerd commented 2 years ago

Summary

EPITI sequences may be very useful for multi-echo denoising. They generate many more echoes and have significantly less spatial distortions. One issue is that neighboring echoes use overlapping k-space data (similar to a sliding window). That means one might get a new echo every few milliseconds, but echoes that are independent and don't use any of the same underlying k-space data may be approximately 10ms apart. When using these data for denoising, we may want to include all the echoes, but this dependence would be required to be accounted for whenever a fit threshold is used.

Additional Detail

There are several publications on the EPITI sequences, but the original and this video on it might be good starting points: Wang F, Dong Z, Reese TG, et al. Echo planar time-resolved imaging (EPTI). Magn Reson Med. 2019;81(6):3599-3615. doi:10.1002/mrm.27673 Fuyixue Wang and Kawin Setsompop: Echo Planar Time-resolved Imaging (EPTI) YouTube summary

Next Steps

tsalo commented 2 years ago

@handwerkerd Have you had a chance to acquire any EPTI data?

handwerkerd commented 2 years ago

Not yet. I'm working on another acquisition project now, but I should follow up on at least getting some EPITI data.