Add CL parameter to pass a custom design matrix to Mageck - Githubissues

MPUSP / nf-core-crispriscreen

Process next generation sequencing data obtained from CRISPRi repression library screenings

MIT License

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Add CL parameter to pass a custom design matrix to Mageck #19

Closed m-jahn closed 1 year ago

m-jahn commented 1 year ago

Description of feature

right now design matrix is constructed from sample sheet using information on condition, time, etc
more or alternative design matrices are possible with Mageck MLE, so users should get possibility to supply their own
see doc page for more info: https://sourceforge.net/p/mageck/wiki/advanced_tutorial/#tutorial-4-make-full-use-of-mageck-mle-for-more-complicated-experimental-design-eg-paired-samples-time-series