MaayanLab / drugmonizome-issues

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The CREEDS libraries seem to report enriched terms but no odds ratio is calculated #33

Closed ekropiwnicki closed 3 years ago

ekropiwnicki commented 3 years ago

After submitting "Example Drug Set 1" there are 100 enriched terms for CREEDS, however, the odds ratio cannot be calculated which prevents the scatter plot from being generated and the bar plots to display odds ratio as NaN. It appears that there is only one overlapping small molecule for terms in this library which may be the reason why.

The CREEDS library itself is very tiny, in addition to KINOMEscan which may affect enrichment results? There is a table here with the amount of drugs and terms that they cover: https://github.com/MaayanLab/Drugmonizome/tree/master/drugsetlibraries

https://user-images.githubusercontent.com/45180650/107267184-89e04a80-6a14-11eb-87d0-d83603f0e2d1.mov