MaayanLab / enrichr_issues

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Different number of total genes in GO gene set in EnrichR and GO data base #58

Open jloske opened 1 year ago

jloske commented 1 year ago

Describe the bug Dear team, thank you very much for this great tool! I have a question. I was looking for the GO:0060333 Type II Interferon mediated signaling pathway. Using the EnrichR Tool I found an overlap of 23 genes with a total number of 68 genes of the gene set. image

I then looked for this particular gene set using the Amigo page and only found 25 genes in total.

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Also when I checked the GSEA page I could only find 25 genes.

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As far as I understand it should be each time the same gene set (same GO-ID, same name, same GOBP 2021 version). However I could not find the full gene set of 68 genes stated in the EnrichR Tool (it´s the same amount in the online tool). Where are the additional genes coming from? I used the species Human.

Any solutiions would be highly appreciated!

Best,

Jenny