MannLabs / alphapeptdeep

Deep learning framework for proteomics
Apache License 2.0
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MS2 tune #19

Closed jalew188 closed 2 years ago

jalew188 commented 2 years ago

After testing on ProteomeTools 21 PTMs, we found out that warmup epoch is also important for ms2 fine-tuning, even for few-shot fine-tuning.

jalew188 commented 2 years ago

image

Comparing with the results those I shared last week in bioinfor meeting, warmup-based fine-tuning has less overfitting issues.

jalew188 commented 2 years ago

Results before:

image

I guess it is not really overfitting, but falling into the local maxima while training with only a few samples.