MannLabs / directlfq

Fast and accurate label-free quantification for small and very large numbers of proteomes
https://doi.org/10.1101/2023.02.17.528962
Apache License 2.0
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Normalisation values are extremly high #16

Closed tomthun closed 1 year ago

tomthun commented 1 year ago

Describe the bug

Its not really a bug but i recognized that the values of the normalisation output are overall very high (around 1e15 to 1e16). I am wondering why this is so. Processing was done with the python version on windows.

To Reproduce

simply run lfq_manager.run_lfq(CustomDf.aq_reformat.txt)

ammarcsj commented 1 year ago

Hi! Thank for reaching out :), I checked but cannot reproduce the issue (see attached file). Could you check if this is maybe a decimal point issue? I.e. the numbers behind the comma might be interpreted as integer parts?

Best Constantin

CustomDf.aq_reformat.tsv.protein_intensities.tsv.zip

tomthun commented 1 year ago

Oh haha yes it is an issue with excel, my bad ^^