MarcElosua / SPOTlight

Spatial Transcriptomics Capture Location Deconvolution
https://marcelosua.github.io/SPOTlight
GNU General Public License v3.0
159 stars 25 forks source link

Difference between cell type correlation and cell communication #78

Closed wang0430 closed 1 year ago

wang0430 commented 1 year ago

Spotlight provides the function to analyze the cell type correlation. I'm curious how this differs from cell communication and what the underlying principle is.

MarcElosua commented 1 year ago

Hi @wang0430

Thank you for your interest in SPOTlight! Cell type correlation just looks at how the predicted proportions of cells correlate within each spot. It does not take into account any Ligand-Receptor information.

Hope this helps, Marc