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Error in Simulx: build model (rethrow) #6

Closed ddmarathe closed 9 years ago

ddmarathe commented 9 years ago

Hello Marc,

After installation of simulator and mlxR files and running an example, I am getting the following error:

Error in simulxunit(model = model, group = group, treatment = treatment, : build module (rethrow) :Cannot load library: C:\Users\MARATHED\lixoft\mlxlibrary\mlxlibrary110\modules\89e10a8f-d538-4f7a-b3eb-f049a029c7b9\15abea6b21524e1a87247ab74fabd4af\lib\libC15abea6b21524e1a87247ab74fabd4afPlugin.dll In addition: Warning message:

package ‘Rcpp’ was built under R version 3.1.3

Also I see that the mlxR package is automatically stored in the following location after installing from package. C:\Users\MARATHED\Documents\R\win-library\3.1 Do I have to import the contents of mlxR to where the mlxlibrary folder is located? Thanks for your help. Regards, -D. Marathe

MarcLavielle commented 9 years ago

dear D. Marathe,

No, you don't need to move mlxR to any other place. but you should install mlxLibrary 1.1.1 from Lixoft website

do you have any error message when you use mlxR from CRAN?

Marc

2015-05-07 19:36 GMT+02:00 ddmarathe notifications@github.com:

Hello Marc, After installation of simulator and mlxR files and running an example, I am getting the following error:

Error in simulxunit(model = model, group = group, treatment = treatment, : build module (rethrow) :Cannot load library: C:\Users\MARATHED\lixoft\mlxlibrary\mlxlibrary110\modules\89e10a8f-d538-4f7a-b3eb-f049a029c7b9\15abea6b21524e1a87247ab74fabd4af\lib\libC15abea6b21524e1a87247ab74fabd4afPlugin.dll In addition: Warning message: package 'Rcpp' was built under R version 3.1.3

Also I see that the mlxR package is automatically stored in the following location after installing from package. C:\Users\MARATHED\Documents\R\win-library\3.1 Do I have to import the contents of mlxR to where the mlxlibrary folder is located? Thanks for your help. Regards, -D. Marathe

Reply to this email directly or view it on GitHub https://github.com/MarcLavielle/mlxR/issues/6.

Mixed Effects Models for the Population Approach http://www.math.u-psud.fr/~lavielle/book.html

Marc Lavielle Inria Saclay

Tel: (33) 1 69 15 57 43 (33) 6 37 31 93 05

Marc.Lavielle@inria.fr http://www.math.u-psud.fr/~lavielle

"""""""""""""""""""""""""""""""""""""""""""""""""""""""""

ddmarathe commented 9 years ago

Dear Marc, I did download and install Simulator from Lixoft website (SimulatorInstall-V111-win64.exe). After that I downloaded mlxR from CRAN once and from Github the next time for testing whether the simulator would work. I did not get any error while loading mlxR from CRAN or from Github, but the simulator throws the above error message. I did notice that I can't find the initMlxLibrary.R anywhere in any of my directories or the whole harddrive. Where is the location of this file typically?

MarcLavielle commented 9 years ago

can you please

1) install mlxR from CRAN

install.packages("mlxR")

2) install mlxLibrary from Lixoft website

http://download.lixoft.com/?software=mlxlibrary

3) run any of the examples

thank you

Marc

2015-05-07 21:20 GMT+02:00 ddmarathe notifications@github.com:

  • initMlxLibrary.R sorry for the typo.

Reply to this email directly or view it on GitHub https://github.com/MarcLavielle/mlxR/issues/6#issuecomment-99987382.

ddmarathe commented 9 years ago

I followed the procedure. Here is the output that I get (my version of R is v3.1.2):

install.packages("mlxR") Installing package into ‘C:/Users/MARATHED/Documents/R/win-library/3.1’ (as ‘lib’ is unspecified) trying URL 'http://watson.nci.nih.gov/cran_mirror/bin/windows/contrib/3.1/mlxR_2.1.1.zip' Content type 'application/zip' length 65420 bytes (63 Kb) opened URL downloaded 63 Kb

package ‘mlxR’ successfully unpacked and MD5 sums checked

The downloaded binary packages are in C:\Users\MARATHED\AppData\Local\Temp\3\RtmpyeDTny\downloaded_packages

library("mlxR") Loading required package: ggplot2 Warning messages: 1: package ‘mlxR’ was built under R version 3.1.3 2: package ‘ggplot2’ was built under R version 3.1.3 setwd("M:\Data\Training\Monolix_Simulations\caseStudies\cts") library(gridExtra) Loading required package: grid Warning message: package ‘gridExtra’ was built under R version 3.1.3 source('titration.R')

adm <- list(time=seq(0,to=440,by=12), amount=20)

ppk <- c(ka_pop=0.4, V_pop=10, k_pop=0.05,

  • omega_ka=0.3, omega_V=0.5, omega_k=0.1, a1=0.05)

g <- list(size=20, level='individual')

Cc <- list(name='Cc', time=seq(0,to=440,by=1)) y1 <- list(name='y1', time=seq(4,to=440,by=24))

s <- list(seed=1234)

res1 <- simulx(model = "model/cts1a.txt",

  • parameter = ppk,
  • treatment = adm,
  • group = g,
  • output = list(Cc, y1),
  • settings = s) Error in simulx(model = "model/cts1a.txt", parameter = ppk, treatment = adm, : build module (rethrow) :Cannot load library: C:\Users\MARATHED\lixoft\mlxlibrary\mlxlibrary110\modules\2004b3a4-1cc9-45c5-bd3b-b6f0856fad43\7fc832f7d8514b349c1f0eada9461772\lib\libC7fc832f7d8514b349c1f0eada9461772Plugin.dll
MarcLavielle commented 9 years ago

did you install mlxLibrary 1.1.1?

it should be installed in C:/ProgramData/Lixoft

do you have this file: C:\Users\MARATHED\lixoft\lixoft.ini

can you copy paste its content please?

2015-05-07 21:51 GMT+02:00 ddmarathe notifications@github.com:

I followed the procedure. Here is the output that I get (my version of R is v3.1.2):

install.packages("mlxR") Installing package into 'C:/Users/MARATHED/Documents/R/win-library/3.1' (as 'lib' is unspecified) trying URL ' http://watson.nci.nih.gov/cran_mirror/bin/windows/contrib/3.1/mlxR_2.1.1.zip ' Content type 'application/zip' length 65420 bytes (63 Kb) opened URL downloaded 63 Kb

package 'mlxR' successfully unpacked and MD5 sums checked

The downloaded binary packages are in C:\Users\MARATHED\AppData\Local\Temp\3\RtmpyeDTny\downloaded_packages

library("mlxR") Loading required package: ggplot2 Warning messages: 1: package 'mlxR' was built under R version 3.1.3 2: package 'ggplot2' was built under R version 3.1.3 setwd("M:\Data\Training\Monolix_Simulations\caseStudies\cts") library(gridExtra) Loading required package: grid Warning message: package 'gridExtra' was built under R version 3.1.3 source('titration.R')

adm <- list(time=seq(0,to=440,by=12), amount=20)

ppk <- c(ka_pop=0.4, V_pop=10, k_pop=0.05,

  • omega_ka=0.3, omega_V=0.5, omega_k=0.1, a1=0.05)

g <- list(size=20, level='individual')

Cc <- list(name='Cc', time=seq(0,to=440,by=1)) y1 <- list(name='y1', time=seq(4,to=440,by=24))

s <- list(seed=1234)

res1 <- simulx(model = "model/cts1a.txt",

  • parameter = ppk,
  • treatment = adm,
  • group = g,
  • output = list(Cc, y1),

  • settings = s) Error in simulx(model = "model/cts1a.txt", parameter = ppk, treatment = adm, : build module (rethrow) :Cannot load library: C:\Users\MARATHED\lixoft\mlxlibrary\mlxlibrary110\modules\2004b3a4-1cc9-45c5-bd3b-b6f0856fad43\7fc832f7d8514b349c1f0eada9461772\lib\libC7fc832f7d8514b349c1f0eada9461772Plugin.dll

    Reply to this email directly or view it on GitHub https://github.com/MarcLavielle/mlxR/issues/6#issuecomment-99995049.

ddmarathe commented 9 years ago

i did install mlxlibrary 1.1.1. Previously I had installed it in default location C:\ProgramData\Lixoft. However I was getting same error message as above. So I had uninstalled it and changed the location of next install to be C:\Users\MARATHED\MlxLibrary1.1.1

Here are the contents of C:\Users\MARATHED\lixoft\lixoft.ini :

[General] Comment=DO NOT MODIFY - Addresses of Lixoft softwares

[softwares] monolix=C:\ProgramData\Monolix\Monolix432s\bin\Monolix_mcr\runtime mlxeditor=C:\ProgramData\Monolix\Monolix432s\bin\Monolix_mcr\runtime\ perlscriptmlx=C:\ProgramData\Monolix\Monolix432s\bin\Monolix_mcr\runtime\ mlxplore=C:\Program Files\MlxPlore\mlxplore111\ mlxlibrary=C:/Users/MARATHED/MlxLibrary1.1.1

MarcLavielle commented 9 years ago

can you please uninstall MlxLibrary from C:/Users/MARATHED/MlxLibrary1.1.1 and install it again in the default folder C:\Users\MARATHED\MlxLibrary1.1.1

2015-05-07 22:08 GMT+02:00 ddmarathe notifications@github.com:

i did install mlxlibrary 1.1.1. Previously I had installed it in default location C:\ProgramData\Lixoft. However I was getting same error message as above. So I had uninstalled it and changed the location of next install to be C:\Users\MARATHED\MlxLibrary1.1.1

Here are the contents of C:\Users\MARATHED\lixoft\lixoft.ini :

[General] Comment=DO NOT MODIFY - Addresses of Lixoft softwares

[softwares] monolix=C:\ProgramData\Monolix\Monolix432s\bin\Monolix_mcr\runtime mlxeditor=C:\ProgramData\Monolix\Monolix432s\bin\Monolix_mcr\runtime\ perlscriptmlx=C:\ProgramData\Monolix\Monolix432s\bin\Monolix_mcr\runtime\ mlxplore=C:\Program Files\MlxPlore\mlxplore111\ mlxlibrary=C:/Users/MARATHED/MlxLibrary1.1.1

Reply to this email directly or view it on GitHub https://github.com/MarcLavielle/mlxR/issues/6#issuecomment-100001512.

ddmarathe commented 9 years ago

Hello Marc, I will try to reset the default location tomorrow with our IT staff, since I do not have the admin access to do the installations. In the mean time, my hunch is that I do not have all the files from mlxR package when I install from CRAN. Under my directory of C:\Users\MARATHED\Documents\R\win-library\3.1\mlxR\R, I see only 3 files, namely, mlxR, mlxR.rdb and mlxR.rdx. But I see on the internet that there are multiple files e.g. inlineModel.R, simulx.R, initMlxLibrary.R etc that should be present in this package (http://rpackages.ianhowson.com/cran/mlxR/). Could you please confirm that I should have these files (or not) under the installed mlxR package?

ddmarathe commented 9 years ago

Ok, I uninstalled both mlxplore and mlxlibrary and reinstalled mlxplore and then mlxlibrary 1.1.1 in their default locations, then installed mlxR package from CRAN and then ran one of the example (cts1.R) that was provided under mlxR210_examples.zip in the Rstudio. Still I get the same error of build module (rethrow). Here is the code and output:

setwd("M:\Data\Training\Monolix_Simulations\caseStudies\cts") library(gridExtra) Loading required package: grid Warning message: package ‘gridExtra’ was built under R version 3.1.3 source('titration.R') adm <- list(time=seq(0,to=440,by=12), amount=20)

ppk <- c(ka_pop=0.4, V_pop=10, k_pop=0.05,

  • omega_ka=0.3, omega_V=0.5, omega_k=0.1, a1=0.05)

g <- list(size=20, level='individual')

Cc <- list(name='Cc', time=seq(0,to=440,by=1)) y1 <- list(name='y1', time=seq(4,to=440,by=24))

s <- list(seed=1234)

res1 <- simulx(model = "model/cts1a.txt",

  • parameter = ppk,
  • treatment = adm,
  • group = g,
  • output = list(Cc, y1),

  • settings = s) Error in simulx(model = "model/cts1a.txt", parameter = ppk, treatment = adm, : build module (rethrow) :Cannot load library: C:\Users\MARATHED\lixoft\mlxlibrary\mlxlibrary110\modules\216d4b96-0a11-46ef-8525-85476c79468c\bd2cd098d5c44abd96401d0e6cb7a616\lib\libCbd2cd098d5c44abd96401d0e6cb7a616Plugin.dll

    Here is the content in the lixoft.ini file: [General] Comment=DO NOT MODIFY - Addresses of Lixoft softwares

[softwares] datxplore=C:\Program Files\DatXPlore\DatXPlore101\ mlxplore=C:\Program Files\MlxPlore\mlxplore111\

mlxlibrary=C:/ProgramData/Lixoft/MlxLibrary1.1.1

I do not know how to troubleshoot next. Thanks.

RaphaelKuate commented 9 years ago

dear D. Marathe, can you send me the results of the following R command Sys.getenv("HOME"), just after the error. Could you check if the file not being loaded (C:\Users\MARATHED\lixoft\mlxlibrary\mlxlibrary110\modules\216d4b96-0a11-46ef-8525-85476c79468c\bd2cd098d5c44abd96401d0e6cb7a616\lib\libCbd2cd098d5c44abd96401d0e6cb7a616Plugin.dll) exists, and could you also send me the result of the following command dir "C:\Users\MARATHED\MlxLibrary1.1.1\tools\MinGW\bin" on a windows console ? Sincerely, Raphaël.

----- Mail original -----

De: "ddmarathe" notifications@github.com À: "MarcLavielle/mlxR" mlxR@noreply.github.com Envoyé: Mercredi 13 Mai 2015 22:03:14 Objet: Re: [mlxR] Error in Simulx: build model (rethrow) (#6)

Ok, I uninstalled both mlxplore and mlxlibrary and reinstalled mlxplore and then mlxlibrary 1.1.1 in their default locations, then installed mlxR package from CRAN and then ran one of the example (cts1.R) that was provided under mlxR210_examples.zip in the Rstudio. Still I get the same error of build module (rethrow). Here is the code and output:

setwd("M:\Data\Training\Monolix_Simulations\caseStudies\cts")

library(gridExtra)

Loading required package: grid

Warning message:

package ‘gridExtra’ was built under R version 3.1.3

source('titration.R')

adm <- list(time=seq(0,to=440,by=12), amount=20)

ppk <- c(ka_pop=0.4, V_pop=10, k_pop=0.05,

  • omega_ka=0.3, omega_V=0.5, omega_k=0.1, a1=0.05)

g <- list(size=20, level='individual')

Cc <- list(name='Cc', time=seq(0,to=440,by=1))

y1 <- list(name='y1', time=seq(4,to=440,by=24))

s <- list(seed=1234)

res1 <- simulx(model = "model/cts1a.txt",

  • parameter = ppk,
  • treatment = adm,
  • group = g,
  • output = list(Cc, y1),
  • settings = s) Error in simulx(model = "model/cts1a.txt", parameter = ppk, treatment = adm, : build module (rethrow) :Cannot load library: C:\Users\MARATHED\lixoft\mlxlibrary\mlxlibrary110\modules\216d4b96-0a11-46ef-8525-85476c79468c\bd2cd098d5c44abd96401d0e6cb7a616\lib\libCbd2cd098d5c44abd96401d0e6cb7a616Plugin.dll ---------- Here is the content in the lixoft.ini file: [General] Comment=DO NOT MODIFY - Addresses of Lixoft softwares

[softwares] datxplore=C:\Program Files\DatXPlore\DatXPlore101\ mlxplore=C:\Program Files\MlxPlore\mlxplore111\ mlxlibrary=C:/ProgramData/Lixoft/MlxLibrary1.1.1

I do not know how to troubleshoot next. Thanks.

— Reply to this email directly or view it on GitHub .

ddmarathe commented 9 years ago

Here you go:

Sys.getenv("HOME") [1] "C:/Users/MARATHED/Documents" Sys.getenv("LIXOFT_HOME") [1] "C:\ProgramData\Lixoft\MlxLibrary1.1.1"

I also changed LIXOFT_HOME path variable to dir where lixoft.ini is located in the next run, but the same error persisted..

Sys.setenv("LIXOFT_HOME" = "C:\Users\MARATHED\lixoft") Sys.getenv("LIXOFT_HOME") [1] "C:\Users\MARATHED\lixoft"

The .dll file in the error indeed exists at the location specified at the above path in the error.

The MlxLibrary1.1.1 folder is not created at C:\Users\MARATHED.. location. During installation of mlxlibrary simulator, the default location of creation of MlxLibrary1.1.1 folder is in C:\ProgramData\Lixoft...

In windows console following command dir "C:\ProgramData\Lixoft\MlxLibrary1.1.1\tools\MinGW\bin"
I get following output:

C:\Users\MARATHED>dir "C:\ProgramData\Lixoft\MlxLibrary1.1.1\tools\MinGW\bin" Volume in drive C is FDA Volume Serial Number is XXXX-XXXX (I am redacting the serial number)

Directory of C:\ProgramData\Lixoft\MlxLibrary1.1.1\tools\MinGW\bin

03/16/2015 04:59 PM

. 03/16/2015 04:59 PM .. 05/31/2013 10:33 PM 871,424 addr2line.exe 05/31/2013 10:33 PM 896,000 ar.exe 05/31/2013 10:33 PM 1,379,840 as.exe 05/31/2013 11:31 PM 1,701,888 c++.exe 05/31/2013 10:33 PM 869,888 c++filt.exe 05/31/2013 11:31 PM 1,700,352 cpp.exe 05/31/2013 10:33 PM 929,792 dlltool.exe 05/31/2013 10:33 PM 74,240 dllwrap.exe 05/31/2013 10:33 PM 59,904 elfedit.exe 05/31/2013 11:31 PM 1,701,888 g++.exe 05/31/2013 11:31 PM 56,832 gcc-ar.exe 05/31/2013 11:32 PM 56,832 gcc-nm.exe 05/31/2013 11:32 PM 56,832 gcc-ranlib.exe 05/31/2013 11:31 PM 1,699,328 gcc.exe 05/31/2013 11:32 PM 1,229,312 gcov.exe 06/01/2013 12:18 AM 77,911 gdb.exe 06/01/2013 12:18 AM 6,618,206 gdborig.exe 06/01/2013 12:18 AM 316,340 gdbserver.exe 05/31/2013 11:33 PM 76,288 gendef.exe 05/31/2013 11:34 PM 93,696 genidl.exe 05/31/2013 11:34 PM 50,688 genpeimg.exe 05/31/2013 11:31 PM 1,701,888 gfortran.exe 05/31/2013 10:33 PM 933,376 gprof.exe 05/31/2013 10:33 PM 1,239,040 ld.bfd.exe 05/31/2013 10:33 PM 1,239,040 ld.exe 05/31/2013 11:31 PM 488,166 libgcc_s_seh-1.dll 05/31/2013 11:31 PM 1,246,463 libgfortran-3.dll 05/31/2013 11:31 PM 79,449 libgomp-1.dll 05/31/2013 11:31 PM 351,039 libquadmath-0.dll 05/31/2013 11:31 PM 41,959 libssp-0.dll 05/31/2013 11:32 PM 965,582 libstdc++-6.dll 05/31/2013 10:21 PM 79,125 libwinpthread-1.dll 07/11/2009 03:34 PM 155,648 mingw32-make.exe 07/11/2009 03:34 PM 734,024 msys-1.0.dll 05/31/2013 10:33 PM 881,152 nm.exe 05/31/2013 10:33 PM 1,039,360 objcopy.exe 05/31/2013 10:33 PM 1,693,696 objdump.exe 05/31/2013 10:33 PM 896,000 ranlib.exe 05/31/2013 10:33 PM 423,936 readelf.exe 05/31/2013 10:33 PM 872,960 size.exe 05/31/2013 10:33 PM 871,936 strings.exe 05/31/2013 10:33 PM 1,039,360 strip.exe 05/31/2013 10:33 PM 894,976 windmc.exe 05/31/2013 10:33 PM 981,504 windres.exe 05/31/2013 11:31 PM 1,701,888 x86_64-w64-mingw32-c++.exe 05/31/2013 11:31 PM 1,701,888 x86_64-w64-mingw32-g++.exe 05/31/2013 11:31 PM 1,699,328 x86_64-w64-mingw32-gcc-4.8.1.exe 05/31/2013 11:31 PM 56,832 x86_64-w64-mingw32-gcc-ar.exe 05/31/2013 11:32 PM 56,832 x86_64-w64-mingw32-gcc-nm.exe 05/31/2013 11:32 PM 56,832 x86_64-w64-mingw32-gcc-ranlib.exe 05/31/2013 11:31 PM 1,699,328 x86_64-w64-mingw32-gcc.exe 05/31/2013 11:31 PM 1,701,888 x86_64-w64-mingw32-gfortran.exe 05/31/2013 11:35 PM 431,104 x86_64-w64-mingw32-widl.exe 53 File(s) 48,473,080 bytes 2 Dir(s) 214,767,104,000 bytes free

C:\Users\MARATHED>

FYI, My MlxPlore does work and I can run basic simulations in it. Its just that I am not able to utilize the power of simulator for trial simulations.

RaphaelKuate commented 9 years ago

Please, do not change the variable LIXOFT_HOME, it must point at the location of MlxLibrary installation. Please could you send me the result of Sys.getenv("PATH"), this variable is use by the loader. Sincerely, Raphaël.

----- Mail original -----

De: "ddmarathe" notifications@github.com À: "MarcLavielle/mlxR" mlxR@noreply.github.com Cc: "RaphaelKuate" raphael.kuate@inria.fr Envoyé: Mercredi 13 Mai 2015 23:19:38 Objet: Re: [mlxR] Error in Simulx: build model (rethrow) (#6)

Here you go:

Sys.getenv("HOME")

[1] "C:/Users/MARATHED/Documents"

Sys.getenv("LIXOFT_HOME")

[1] "C:\ProgramData\Lixoft\MlxLibrary1.1.1"

I also changed LIXOFT_HOME path variable to dir where lixoft.ini is located in the next run, but the same error persisted..

Sys.setenv("LIXOFT_HOME" = "C:\Users\MARATHED\lixoft")

Sys.getenv("LIXOFT_HOME")

[1] "C:\Users\MARATHED\lixoft"

The .dll file in the error indeed exists at the location specified at the above path in the error.

The MlxLibrary1.1.1 folder is not created at C:\Users\MARATHED.. location. During installation of mlxlibrary simulator, the default location of creation of MlxLibrary1.1.1 folder is in C:\ProgramData\Lixoft...

In windows console following command dir "C:\ProgramData\Lixoft\MlxLibrary1.1.1\tools\MinGW\bin"

I get following output:

C:\Users\MARATHED>dir "C:\ProgramData\Lixoft\MlxLibrary1.1.1\tools\MinGW\bin" Volume in drive C is FDA Volume Serial Number is XXXX-XXXX (I am redacting the serial number)

Directory of C:\ProgramData\Lixoft\MlxLibrary1.1.1\tools\MinGW\bin

03/16/2015 04:59 PM . 03/16/2015 04:59 PM .. 05/31/2013 10:33 PM 871,424 addr2line.exe 05/31/2013 10:33 PM 896,000 ar.exe 05/31/2013 10:33 PM 1,379,840 as.exe 05/31/2013 11:31 PM 1,701,888 c++.exe 05/31/2013 10:33 PM 869,888 c++filt.exe 05/31/2013 11:31 PM 1,700,352 cpp.exe 05/31/2013 10:33 PM 929,792 dlltool.exe 05/31/2013 10:33 PM 74,240 dllwrap.exe 05/31/2013 10:33 PM 59,904 elfedit.exe 05/31/2013 11:31 PM 1,701,888 g++.exe 05/31/2013 11:31 PM 56,832 gcc-ar.exe 05/31/2013 11:32 PM 56,832 gcc-nm.exe 05/31/2013 11:32 PM 56,832 gcc-ranlib.exe 05/31/2013 11:31 PM 1,699,328 gcc.exe 05/31/2013 11:32 PM 1,229,312 gcov.exe 06/01/2013 12:18 AM 77,911 gdb.exe 06/01/2013 12:18 AM 6,618,206 gdborig.exe 06/01/2013 12:18 AM 316,340 gdbserver.exe 05/31/2013 11:33 PM 76,288 gendef.exe 05/31/2013 11:34 PM 93,696 genidl.exe 05/31/2013 11:34 PM 50,688 genpeimg.exe 05/31/2013 11:31 PM 1,701,888 gfortran.exe 05/31/2013 10:33 PM 933,376 gprof.exe 05/31/2013 10:33 PM 1,239,040 ld.bfd.exe 05/31/2013 10:33 PM 1,239,040 ld.exe 05/31/2013 11:31 PM 488,166 libgcc_s_seh-1.dll 05/31/2013 11:31 PM 1,246,463 libgfortran-3.dll 05/31/2013 11:31 PM 79,449 libgomp-1.dll 05/31/2013 11:31 PM 351,039 libquadmath-0.dll 05/31/2013 11:31 PM 41,959 libssp-0.dll 05/31/2013 11:32 PM 965,582 libstdc++-6.dll 05/31/2013 10:21 PM 79,125 libwinpthread-1.dll 07/11/2009 03:34 PM 155,648 mingw32-make.exe 07/11/2009 03:34 PM 734,024 msys-1.0.dll 05/31/2013 10:33 PM 881,152 nm.exe 05/31/2013 10:33 PM 1,039,360 objcopy.exe 05/31/2013 10:33 PM 1,693,696 objdump.exe 05/31/2013 10:33 PM 896,000 ranlib.exe 05/31/2013 10:33 PM 423,936 readelf.exe 05/31/2013 10:33 PM 872,960 size.exe 05/31/2013 10:33 PM 871,936 strings.exe 05/31/2013 10:33 PM 1,039,360 strip.exe 05/31/2013 10:33 PM 894,976 windmc.exe 05/31/2013 10:33 PM 981,504 windres.exe 05/31/2013 11:31 PM 1,701,888 x86_64-w64-mingw32-c++.exe 05/31/2013 11:31 PM 1,701,888 x86_64-w64-mingw32-g++.exe 05/31/2013 11:31 PM 1,699,328 x86_64-w64-mingw32-gcc-4.8.1.exe 05/31/2013 11:31 PM 56,832 x86_64-w64-mingw32-gcc-ar.exe 05/31/2013 11:32 PM 56,832 x86_64-w64-mingw32-gcc-nm.exe 05/31/2013 11:32 PM 56,832 x86_64-w64-mingw32-gcc-ranlib.exe 05/31/2013 11:31 PM 1,699,328 x86_64-w64-mingw32-gcc.exe 05/31/2013 11:31 PM 1,701,888 x86_64-w64-mingw32-gfortran.exe 05/31/2013 11:35 PM 431,104 x86_64-w64-mingw32-widl.exe 53 File(s) 48,473,080 bytes 2 Dir(s) 214,767,104,000 bytes free

C:\Users\MARATHED>

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ddmarathe commented 9 years ago

ok, I will reset LIXOFT_HOME path as you suggested. But in response to another issue Marc had suggested to point the LIXOFT_HOME path to where lixoft.ini is located, that is why I tried that alternative when I was getting the error.

Here is the env. variable for PATH:

Sys.getenv("PATH") [1] "C:\Program Files\R\R-3.1.2\bin\x64;C:\PHSTMinGW\bin;C:\Program Files (x86)\Pharsight\Phoenix\application\lib\NLME\Executables\;C:\Program Files (x86)\TIBCO\splus81\;C:\Ora10g\bin;C:\WINDOWS\system32;C:\WINDOWS;C:\WINDOWS\System32\Wbem;C:\WINDOWS\System32\WindowsPowerShell\v1.0\;\"C:\Program Files (x86)\Common Files\EMC\";C:\Program Files\ActivIdentity\ActivClient\;C:\Program Files (x86)\ActivIdentity\ActivClient\;C:\Program Files\MATLAB\R2012b\bin;C:\Program Files (x86)\WebEx\Productivity Tools;C:\ProgramData\Lixoft\MlxLibrary1.1.1/tools/MinGW/bin"

RaphaelKuate commented 9 years ago

I see... you have another MinGW in your PATH, it may be the cause of conflicts with the MinGW of Lixoft, so could you remove C:\PHSTMinGW\bin from your PATH and try again?

Raphaël.

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De: "ddmarathe" notifications@github.com À: "MarcLavielle/mlxR" mlxR@noreply.github.com Cc: "RaphaelKuate" raphael.kuate@inria.fr Envoyé: Mercredi 13 Mai 2015 23:33:35 Objet: Re: [mlxR] Error in Simulx: build model (rethrow) (#6)

ok, I will reset LIXOFT_HOME path as you suggested. But in response to another issue Marc had suggested to point the LIXOFT_HOME path to where lixoft.ini is located, that is why I tried that alternative when I was getting the error.

Here is the env. variable for PATH:

Sys.getenv("PATH")

[1] "C:\Program Files\R\R-3.1.2\bin\x64;C:\PHSTMinGW\bin;C:\Program Files (x86)\Pharsight\Phoenix\application\lib\NLME\Executables\;C:\Program Files (x86)\TIBCO\splus81\;C:\Ora10g\bin;C:\WINDOWS\system32;C:\WINDOWS;C:\WINDOWS\System32\Wbem;C:\WINDOWS\System32\WindowsPowerShell\v1.0\;\"C:\Program Files (x86)\Common Files\EMC\";C:\Program Files\ActivIdentity\ActivClient\;C:\Program Files (x86)\ActivIdentity\ActivClient\;C:\Program Files\MATLAB\R2012b\bin;C:\Program Files (x86)\WebEx\Productivity Tools;C:\ProgramData\Lixoft\MlxLibrary1.1.1/tools/MinGW/bin"

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ddmarathe commented 9 years ago

You are a genius!

I did not remove PHSTmin, but I appended the Mlxlibrary MinGW path so that it comes before MinGW in PHST (Phoenix s/w) and the error is gone and I am getting the output of simulation that I could verify with plotting function. Thanks much!

Sys.setenv( PATH = paste( "C:\ProgramData\Lixoft\MlxLibrary1.1.1\tools\MinGW\bin", Sys.getenv("PATH"), sep = ";" )

)

ddmarathe commented 9 years ago

Thank you for helping me towards troubleshooting and solving the problem, Raphael, Marc and Devin. I am closing the issue.