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MarioniLab / miloR

R package implementation of Milo for testing for differential abundance in KNN graphs
https://bioconductor.org/packages/release/bioc/html/miloR.html
GNU General Public License v3.0
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Log10 FC or Log2 FC? #336

Closed mainharryHR closed 1 day ago

mainharryHR commented 3 months ago

Dear MilloR team,

I know in the paper, it is clearly claimed Log FC (= Log10 FC), I am writing to confirm that it is not Log2 FC?. If we see LogFC=3, it means there are 1000 differences, which sounds a lot to me :).

Many thanks for the nice package.

Best, Nic

MikeDMorgan commented 3 months ago

Hi @mainharryHR It is the natural log, not base 10 or 2, so a LFC=3 is a fold-change of exp(3) $\approx$ 20.