Closed salvatta2 closed 1 year ago
Hi @salvatta2 sorry for the late reply. You can use "Kabat + Vernier" CDR definition in the settings, this will avoid any mutations in those regions.
Hi David, many thanks for your reply, sorry my fault I didn't see this on the web server. Now clear! Kind regards, Salva
On Sat, 15 Oct 2022 at 13:58, David Příhoda @.***> wrote:
Hi @salvatta2 https://github.com/salvatta2 sorry for the late reply. You can use "Kabat + Vernier" CDR definition in the settings, this will avoid any mutations in those regions.
[image: image] https://user-images.githubusercontent.com/2894124/195985191-d87c6895-1312-472c-96e9-0d6e42d418e5.png
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Hi, I see that the CDR grafting option in the server performs straight grafting. Is there any way to automatically perform "Vernier" CDR grafting while retaining key "back-mutations" in the Vernier zones (as you describe in the paper)? Thank you!! SG