BioPhi is an open-source antibody design platform. It features methods for automated antibody humanization (Sapiens), humanness evaluation (OASis) and an interface for computer-assisted antibody sequence design.
Just for information and to help other users of Biophi:
I installed Biophi using miniforge by following instructions provided on the project's github page.
However there was a runtime error:
AttributeError: 'Engine' object has no attribute 'execute'
I could track the issue down to a change in Sqlalchemy 2.0. Downgrading to Sqlalchemy via conda did the trick:
https://docs.sqlalchemy.org/en/14/changelog/migration_20.html
It is about engine.execute() which was deprecated in 1.4 and removed in 2.0.
$ conda install "sqlalchemy<2.0"
That installed sqlalchemy-1.4.46.
Kind regards and many thanks for providing Biophi, a great application!
Just for information and to help other users of Biophi:
I installed Biophi using miniforge by following instructions provided on the project's github page. However there was a runtime error: AttributeError: 'Engine' object has no attribute 'execute'
I could track the issue down to a change in Sqlalchemy 2.0. Downgrading to Sqlalchemy via conda did the trick: https://docs.sqlalchemy.org/en/14/changelog/migration_20.html It is about engine.execute() which was deprecated in 1.4 and removed in 2.0.
$ conda install "sqlalchemy<2.0" That installed sqlalchemy-1.4.46.
Kind regards and many thanks for providing Biophi, a great application!