I now believe there might be a bug in my original code for heuristically handling phosphorylated compounds. I haven't got the time at the moment to follow up on this, but we will be migrating that code into Python, in this repository, and re-running it to double-check for any problems such as this one.
I've just discovered two pairs of reactions that use NADH and NADPH but deltaG is wrong for the second (NADPH) one:
I now believe there might be a bug in my original code for heuristically handling phosphorylated compounds. I haven't got the time at the moment to follow up on this, but we will be migrating that code into Python, in this repository, and re-running it to double-check for any problems such as this one.