Less of a priority than #69 and #70, so let's say it is blocked on that. But this basically means re-creating the fitting process in https://doi.org/10.1016/j.bpj.2019.07.029 in WL.
Which involves at least a two step fitting process:
i) fitting hERG kinetics (same model as #69 with a tweaked fitting spec for a different protocol) to a load of different traces (N=124).
ii) taking a mean (in a transformed space) of these parameters as the eventual consensus kinetics.
Less of a priority than #69 and #70, so let's say it is blocked on that. But this basically means re-creating the fitting process in https://doi.org/10.1016/j.bpj.2019.07.029 in WL.
Which involves at least a two step fitting process: i) fitting hERG kinetics (same model as #69 with a tweaked fitting spec for a different protocol) to a load of different traces (N=124). ii) taking a mean (in a transformed space) of these parameters as the eventual consensus kinetics.