Open ewels opened 7 years ago
Hello @ewels ,
Here's an example for that PLINK/SEQ run.
The goal here is to see if there's an imbalance in what we are expecting from a sample in term of the ratio for the homozygous alternative allele vs heterozygous alleles. To get this, just infer the homozygous from the column NHET and NVAR : NHOMALT=(NVAR - NHET) and do the ratio with the NHET : NHOMALT/NHET. If a sample is completely out of the average, it means there's probably a library issue or that this sample his having something special.
Runs_278-279.merge.miss50.istats.txt
JC
Requested in #311 by @jcgrenier: